Selection of mutant strain of Penicillium funiculosum for (-)-mitorubrinic acid production

被引：0

作者：

Lesová, K ^{[1
]}

Sturdíková, M ^{[1
]}

Tybitanclová, K ^{[1
]}

机构：

[1] Slovak Univ Technol Bratislava, Fac Chem Technol, Dept Biochem Technol, SK-81237 Bratislava, Slovakia

来源：

BIOLOGIA | 2000年 / 55卷 / 06期

关键词：

Penicillium funiculosum; mutation; (-)-mitorubrinic acid;

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The strain of Penicillium funiculosum for the production of (-)-mitorubrinic acid was prepared hy mutation from the parental strain Penicillium funiculosum CCM F-8080 with production of (-)-mitorubrinic acid 175 mg/L. Ultraviolet radiation and N-nitroso-N-methyl-urea were used as mutagen agents. The mutant strain of Penicillium funiculosum was selected and the production of (-)-mitorubrinic acid increased from 443.4 to 728.7 mg/L. Also the mutant strain with blocked production of (-)-mitorubrinic acid and the strain with ability to produce some new orange metabolites were prepared.

引用

页码：633 / 636

页数：4

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