Cerpegin alkaloid and its analogues: Chemical synthesis and pharmacological profiles

被引:0
|
作者
Basak, Sankar [1 ]
机构
[1] Siliguri Coll, Dept Chem, Darjeeling 734001, W Bengal, India
关键词
Cerpegin alkaloid; Ceropegia plant; metalation; proteasome inhibitor; analgesic; antiurolithiatic; antidiabetic; 20S PROTEASOME; N-5; DERIVATIVES; WESTERN-GHATS; CORE PARTICLE; CEROPEGIA; SERIES; REGENERATION; INHIBITION;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This review aims to highlight cerpegin alkaloid, a key compound of the genus Ceropegia. It shows significant biological activities and a number of synthetic strategies for synthesis of cerpegin alkaloid have been reported. In recent years its derivatives have raised interest as promising bioactive candidates to explore and improve its pharmacological profile. It is anticipated that this area of chemistry will continue to attract significant research activity in future.
引用
收藏
页码:1175 / 1190
页数:16
相关论文
共 50 条
  • [41] Synthesis of Pharmacological Relevant 1,2,3-Triazole and its Analogues-A Review
    Varala, Ravi
    Bollikolla, Hari Babu
    Kurmarayuni, Chandra Mohan
    CURRENT ORGANIC SYNTHESIS, 2021, 18 (02) : 101 - 124
  • [42] Galanin and its analogues modified in position 14: Chemical synthesis and biological activity
    Ruczynski, J
    Szyk, A
    Konstanski, Z
    Korolkiewicz, R
    Rekowski, P
    POLISH JOURNAL OF CHEMISTRY, 2000, 74 (10) : 1375 - 1384
  • [43] Chemical Synthesis and Antitumor Evaluation of Chikusetsusaponin IVa Butyl Ester and Its Analogues
    Zheng, Jibin
    Wang, Yanxiao
    Zhang, Yiyue
    Rong, Jingjing
    He, Dongjuan
    Wang, Xiaotong
    Zhang, Liangliang
    Xu, Jiangang
    Cao, Peng
    Yang, You
    SYNLETT, 2024,
  • [44] Synthesis and pharmacological studies of new pyrazole analogues of podophyllotoxin
    B. Umesha
    Y. B. Basavaraju
    Russian Journal of Bioorganic Chemistry, 2014, 40 : 467 - 476
  • [45] Synthesis and Pharmacological Properties of New Tetracyclic Forskolin Analogues
    Egger, Michael
    Maity, Prantik
    Huebner, Melanie
    Seifert, Roland
    Koenig, Burkhard
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2009, 2009 (21) : 3613 - 3618
  • [46] The Synthesis of Epiboxidine and Related Analogues as Potential Pharmacological Agents
    Kulu, Irem
    Ocal, Nuket
    HELVETICA CHIMICA ACTA, 2011, 94 (11) : 2054 - 2060
  • [47] Concise Synthesis and Pharmacological Applications of New α-Lapachone Analogues
    Hamama, Wafaa S.
    Hassanien, Alaa E.
    Zoorob, Hanafi H.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (01) : 282 - 290
  • [48] SYNTHESIS OF ANALOGUES AND DERIVATIVES OF RADICININ OF POTENTIAL PHARMACOLOGICAL INTEREST
    BIGLINO, G
    CATTEL, L
    NOBILI, G
    CAPUTO, O
    FARMACO-EDIZIONE SCIENTIFICA, 1970, 25 (02): : 145 - &
  • [49] Synthesis and pharmacological studies of new pyrazole analogues of podophyllotoxin
    Umesha, B.
    Basavaraju, Y. B.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2014, 40 (04) : 467 - 476
  • [50] Synthesis of marine alkaloid: 8,9-dihydrocoscinamide B and its analogues as Novel class of antileishmanial agents
    Gupta, Leena
    Talwar, Archna
    Nishi
    Palne, Shraddha
    Gupta, Suman
    Chauhan, Prern M. S.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (14) : 4075 - 4079