Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual

被引：2

作者：

Fuchs, Nina, V ^{[1
]}

Schieck, Maximilian ^{[2
]}

Neuenkirch, Michaela ^{[1
]}

Tondera, Christiane ^{[1
]}

Schmitz, Heike ^{[1
]}

Steinemann, Doris ^{[2
]}

Goehring, Gudrun ^{[2
]}

Koenig, Renate ^{[1
,3
]}

机构：

[1] Paul Ehrlich Inst, Host Pathogen Interact, D-63225 Langen, Germany

[2] Hannover Med Sch, Dept Human Genet, Hannover, Germany

[3] Sanford Burnham Prebys Med Discovery Inst, Immun & Pathogenesis Program, La Jolla, CA 92037 USA

来源：

STEM CELL RESEARCH | 2020年 / 42卷

关键词：

Induced pluripotent stem cells from an apparently healthy individual; Induced Pluripotent stem cells capable of differentiation into all three germ layers;

D O I：

10.1016/j.scr.2019.101679

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Induced pluripotent stem cells (iPSCs) are a useful tool to investigate pathomechanistic and cellular processes due to their differentiation potential into different somatic cell types in vitro. Here, we have generated iPSCs from an apparently healthy male individual using an integration-free reprogramming method. The resulting iPSCs are pluripotent and display a normal karyotype. Furthermore, we demonstrate that this iPSC line can be differentiated into all three germ layers.

引用

页数：4

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