Cerebral Hemorrhage and Alcohol Exposure: A Review

被引：22

作者：

Peng, Jialing ^{[1
]}

Wang, Hongxuan ^{[1
]}

Rong, Xiaoming ^{[1
]}

He, Lei ^{[1
]}

Xiangpen, L. ^{[1
]}

Shen, Qingy ^{[1
]}

Peng, Ying ^{[1
,2
]}

机构：

[1] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Neurol, 33 Yinfeng Rd, Guangzhou 510828, Peoples R China

[2] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangdong Prov Key Lab Malignant Tumor Epigenet &, 33 Yinfeng Rd, Guangzhou, Peoples R China

来源：

ALCOHOL AND ALCOHOLISM | 2020年 / 55卷 / 01期

基金：

中国国家自然科学基金;

关键词：

CHRONIC ETHANOL-CONSUMPTION; CORONARY-HEART-DISEASE; LIFE-STYLE FACTORS; INTRACEREBRAL HEMORRHAGE; RISK-FACTORS; STROKE INCIDENCE; GENDER-DIFFERENCES; SUBARACHNOID HEMORRHAGE; OXIDATIVE STRESS; ISCHEMIC-STROKE;

D O I：

10.1093/alcalc/agz087

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Aims: To investigate the dose-response relationships between alcohol and intracerebral hemorrhage (ICH), the impact of alcohol on the outcome of ICH and possible mechanisms underlying hypertensive ICH (HICH) caused by heavy drinking. Methods: Literature search from 1985 to August 2019 in the PubMed database. Results: The relationship between low-middle alcohol consumption and ICH remains controversial for various reasons, whereas chronic heavy drinking increases the incidence of ICH and exerts worse outcome. More attention is needed to clarify the characteristics of chronic alcohol intake and binge drinking. Chronic alcohol abuse tends to elevates blood pressure, resulting in increased occurrence of HICH and exaggerated HICH-contributed brain injury. Conclusion: It is important to develop strategies to promote reasonable intake categories, prevent alcoholism and thus reduce the risk of ICH.

引用

页码：20 / 27

页数：8

共 50 条

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