Impact of insomnia and obstructive sleep apnea on the risk of acute exacerbation of chronic obstructive pulmonary disease

被引：15

作者：

Li, Shi Qi ^{[1
,2
]}

Sun, Xian Wen ^{[1
,2
]}

Zhang, Liu ^{[1
,2
]}

Ding, Yong Jie ^{[1
,2
]}

Li, Hong Peng ^{[1
,2
]}

Yan, Ya Ru ^{[1
,2
]}

Lin, Ying Ni ^{[1
,2
]}

Zhou, Jian Ping ^{[1
,2
]}

Li, Qing Yun ^{[1
,2
]}

机构：

[1] Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Resp & Crit Care Med, Sch Med, Shanghai 200025, Peoples R China

[2] Shanghai Jiao Tong Univ, Inst Resp Med, Sch Med, Shanghai 200025, Peoples R China

来源：

SLEEP MEDICINE REVIEWS | 2021年 / 58卷

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

Chronic obstructive pulmonary disease; Exacerbation; Insomnia; Obstructive sleep apnea; COGNITIVE-BEHAVIORAL THERAPY; OXIDATIVE STRESS; OVERLAP SYNDROME; OLDER-ADULTS; AIRWAY INFLAMMATION; BENZODIAZEPINE USE; COPD PATIENTS; PREVALENCE; MODERATE; OUTCOMES;

D O I：

10.1016/j.smrv.2021.101444

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Chronic obstructive pulmonary disease (COPD) is a major health burden worldwide. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is characterized by worsening of patients' respiratory symptoms that requires a modification in medication. This event could accelerate disease progression and increase the risk of hospital admissions and mortality. Both insomnia and obstructive sleep apnea (OSA) are prevalent in patients with COPD, and are linked to increased susceptibility to AECOPD. Improper treatment of insomnia may increase the risk of adverse respiratory outcomes for patients with COPD, while effective continuous positive airway pressure (CPAP) treatment may reduce the risk of AECOPD and mortality in patients with overlap syndrome. Sleep disorders should be considered in clinical management for COPD. (C) 2021 Elsevier Ltd. All rights reserved.

引用

页数：12

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