MWNTs are reacted with CM-beta-CD to obtain CM-beta-CD-g-MWNTs with great dispersivity. The effects of pH value, initial concentration of uranium, contact time and adsorbent dosage on the adsorption behavior were investigated. The results show that pH= 5, the initial concentration of uranium was 10mg/L, the adsorption of uranium on CM-beta-CD-g-MWNTs after 90 min, and the adsorption capacity is 19.42 mg/g at 25 degrees C. Kinetics and isothermal were better fitted by Langmuir isotherm model and pseudo-second-order kinetic model, and the maximum adsorption capacity was 92.65mg/g. The composites had been antegrallty made, the -C=O,-C-O and -OH palyed irreplaceable role by SEM, EDS and FTIR.