Multicomponent reactions of ammonium thiocyanate, acyl chlorides, alkyl bromides, and enaminones: A facile one-pot synthesis of thiophenes

被引：13
|
作者：
Hossaini, Zinatossadat [1 ]
Rostami-Charati, Faramarz [2 ]
Soltani, Samira [1 ]
Mirzaei, Anwar [3 ]
Berijani, Kayhaneh [1 ]
机构：
[1] Islamic Azad Univ, Dept Chem, Qaemshahr Branch, Qaemshahr, Iran
[2] Gonbad Kavous Univ, Dept Chem, Fac Sci, Gonbad, Iran
[3] Islamic Azad Univ, Dept Chem, Sanandaj Branch, Sanandaj, Iran
来源：
MOLECULAR DIVERSITY | 2011年 / 15卷 / 04期
关键词：
Thiophene; Ammonium thiocyanate; Carbonyl compounds; Solvent-free conditions; SUBSTITUTED THIOPHENES;
D O I：
10.1007/s11030-011-9322-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
An efficient synthesis of thiophene derivatives is described via one-pot reaction between ammonium thiocyanate, acyl chlorides, alpha-halocarbonyls, and enaminones under solvent-free conditions at 65 degrees C. The mild reaction conditions and high yields of the products exhibit the good synthetic advantage of these methods.
引用
收藏
页码：911 / 916
页数：6
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