A Convenient and Efficient Method for the Synthesis of a Novel Series of N-Butyl-1,4-oxazino[2′,3′:4,5]pyrano[3,2-c] quinolinones

被引：4
|
作者：
Hassanin, Hany M. [1 ]
Hassan, Mohamed M. [1 ]
机构：
[1] Ain Shams Univ, Fac Educ, Dept Chem, Cairo 11711, Egypt
来源：
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2018年 / 29卷 / 04期
关键词：
oxazin; pyrane; quinolinone; heterocyclization; heteroannulation; SOLVENT-FREE; DERIVATIVES;
D O I：
10.21577/0103-5053.20170202
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We design and describe here a simple route for the synthesis of a new multi heterocycle fused 1,4-oxazinopyranoquinolinones compatible with many functional groups. This method proceeds through various cyclic condensation reactions of (3-amino or 3-nitropyrano)[3,2-c] quinoline-2,5(6H)-dione precursors with different 1,2-bifunctional electrophiles. The synthesized compounds are confirmed by infrared (IR), proton (H-1) and carbon-13 (C-13) nuclear magnetic resonance (NMR) spectroscopy and electrospray ionization mass spectrometry (ESI-MS).
引用
收藏
页码：792 / 800
页数：9
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