Corticobasal syndrome;
Transcranial magnetic stimulation;
Cortical excitability;
Treatment;
Slow repetitive transcranial magnetic stimulation;
TMS;
D O I:
10.1007/s10072-015-2115-3
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Corticobasal syndrome is characterized by asymmetric cortical sensorimotor dysfunction and parkinsonism; an altered cortical excitability has been reported. We explored with transcranial magnetic stimulation the motor cortical excitability in corticobasal syndrome, and the effects of slow repetitive transcranial magnetic stimulation. With transcranial magnetic stimulation, we studied two corticobasal syndrome patients. We determined bilaterally from the first dorsal interosseous muscle: relaxed threshold, and contralateral and ipsilateral silent period. We also evaluated the contralateral silent period after active/sham slow repetitive transcranial magnetic stimulation on the most affected side. At T0 the silent period was bilaterally short. On the most affected side, active slow repetitive transcranial magnetic stimulation induced a short lasting prolongation of the contralateral silent period. In corticobasal syndrome, transcranial magnetic stimulation showed a reduction cortical inhibitory phenomenon potentially reversed transiently by slow repetitive transcranial magnetic stimulation.
机构:
Capital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Shenzhen Univ, Gen Hosp, Dept Neurosurg, Shenzhen, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Fu, Mengmeng
Wei, Hua
论文数: 0引用数: 0
h-index: 0
机构:
Capital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Beijing Key Lab Neuromodulat, Beijing, Peoples R China
Capital Med Univ, Minist Sci & Technol, Beijing Inst Brain Disorders, Ctr Epilepsy, Beijing, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Wei, Hua
Meng, Xianghong
论文数: 0引用数: 0
h-index: 0
机构:
Shenzhen Univ, Gen Hosp, Dept Neurosurg, Shenzhen, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Meng, Xianghong
Chen, Hai
论文数: 0引用数: 0
h-index: 0
机构:
Capital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Beijing Key Lab Neuromodulat, Beijing, Peoples R China
Capital Med Univ, Minist Sci & Technol, Beijing Inst Brain Disorders, Ctr Epilepsy, Beijing, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Chen, Hai
Shang, Baoxiang
论文数: 0引用数: 0
h-index: 0
机构:
Shenzhen Univ, Gen Hosp, Dept Neurosurg, Shenzhen, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Shang, Baoxiang
Chen, Fuyong
论文数: 0引用数: 0
h-index: 0
机构:
Shenzhen Univ, Gen Hosp, Dept Neurosurg, Shenzhen, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Chen, Fuyong
Huang, Zhaoyang
论文数: 0引用数: 0
h-index: 0
机构:
Capital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Beijing Key Lab Neuromodulat, Beijing, Peoples R China
Capital Med Univ, Minist Sci & Technol, Beijing Inst Brain Disorders, Ctr Epilepsy, Beijing, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Huang, Zhaoyang
Sun, Ying
论文数: 0引用数: 0
h-index: 0
机构:
Capital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Beijing Key Lab Neuromodulat, Beijing, Peoples R China
Capital Med Univ, Minist Sci & Technol, Beijing Inst Brain Disorders, Ctr Epilepsy, Beijing, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Sun, Ying
Wang, Yuping
论文数: 0引用数: 0
h-index: 0
机构:
Capital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
Beijing Key Lab Neuromodulat, Beijing, Peoples R China
Capital Med Univ, Minist Sci & Technol, Beijing Inst Brain Disorders, Ctr Epilepsy, Beijing, Peoples R ChinaCapital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China
机构:
Univ Milan, Osped Maggiore Policlin Mangiagalli & Regina Elen, Ctr Clin Neuronanotecnol & Neurostimolaz, Dipartimento Sci Neurol,Fdn IRCCS, I-20122 Milan, ItalyUniv Milan, Osped Maggiore Policlin Mangiagalli & Regina Elen, Ctr Clin Neuronanotecnol & Neurostimolaz, Dipartimento Sci Neurol,Fdn IRCCS, I-20122 Milan, Italy
Priori, Aberto
Hallett, Mark
论文数: 0引用数: 0
h-index: 0
机构:
NINDS, Human Motor Control Sect, Bethesda, MD 20892 USAUniv Milan, Osped Maggiore Policlin Mangiagalli & Regina Elen, Ctr Clin Neuronanotecnol & Neurostimolaz, Dipartimento Sci Neurol,Fdn IRCCS, I-20122 Milan, Italy
Hallett, Mark
Rothwell, John C.
论文数: 0引用数: 0
h-index: 0
机构:
ULC, Inst Neurol, Sobell Dept, London, EnglandUniv Milan, Osped Maggiore Policlin Mangiagalli & Regina Elen, Ctr Clin Neuronanotecnol & Neurostimolaz, Dipartimento Sci Neurol,Fdn IRCCS, I-20122 Milan, Italy