Rapid prototyping of cyclic olefin copolymer based microfluidic system with CO2 laser ablation

被引:21
|
作者
Cai, Jianchen [1 ]
Jiang, Jinyun [1 ]
Gao, Feng [2 ]
Jia, Guangnan [2 ]
Zhuang, Jian [2 ]
Tang, Gang [2 ]
Fan, Yiqiang [2 ]
机构
[1] Quzhou Univ, Coll Mech Engn, Quzhou 324000, Zhejiang, Peoples R China
[2] Beijing Univ Chem Technol, Coll Mech & Elect Engn, Beijing 100029, Peoples R China
基金
中国国家自然科学基金;
关键词
CHIP; DEVICE; CELLS; PDMS;
D O I
10.1007/s00542-017-3282-3
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Cyclic olefin copolymer (COC) has high chemical resistance with low water absorption and good optical transparency in visual and near UV range, which is a promising material for the polymer-based microfluidic systems. A comprehensive method for the rapid prototyping of COC based microfluidic system using CO2 laser ablation was proposed in this study. The COC substrate was fabricated by injection molding with a commercial injection molding machine, then CO2 laser was used for direct laser ablation of microchannels on the surface of COC substrate, to seal the laser ablated microchannels, the thermal compression bonding method for COC-based substrates was also provided in this research. The profile of the microchannels was carefully studied with different laser ablation power and scan speed, microfluidic device fabricated using the proposed method were also presented in this research.
引用
收藏
页码:5063 / 5069
页数:7
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