Surgical treatment in ovarian cancer prevention in carriers of the BRCA1/BRCA2 mutation

被引:0
|
作者
Synowiec, Agnieszka [1 ]
Wcislo, Gabriel [1 ]
Bodnar, Lubomir [1 ]
Szczylik, Cezary [1 ]
机构
[1] Wojskowy Inst Med Warszawie, Klin Onkol, Warsaw, Poland
关键词
BRCA1; BRCA2; ovarian cancer; prophylaxis bilateral salpingo-oophovectomy; REDUCING SALPINGO-OOPHORECTOMY; PROPHYLACTIC OOPHORECTOMY; BREAST-CANCER; HEREDITARY BREAST; FALLOPIAN-TUBE; RISK REDUCTION; BRCA1; WOMEN; SURGERY; STATEMENT;
D O I
暂无
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Ovarian cancer remains to be a real challenge in spite of considerable progress in many areas of modern medicine. The use of genetic testing for detecting mutations of the BRCA genes has been offering clinical scrutiny between mutated versions of the BRCA genes and higher risk of both breast and ovarian cancer A population survey is a method of choice to find out more efficient screening management in order to identify cancer patients who further will be treated effectively early. A review of literature on surgical PBSO (prophylactic bilateral salpingooophorectomy) in the BRCA genes mutations carriers with focus on preventive results against morbidity of ovarian cancer has been presented in the article.
引用
收藏
页码:51 / 56
页数:6
相关论文
共 50 条
  • [31] Anthropometric Measures and Risk of Ovarian Cancer Among BRCA1 and BRCA2 Mutation Carriers
    McGee, Jacob
    Kotsopoulos, Joanne
    Lubinski, Jan
    Lynch, Henry T.
    Rosen, Barry
    Tung, Nadine
    Kim-Sing, Charmaine
    Karlan, Beth
    Foulkes, William D.
    Ainsworth, Peter
    Ghadirian, Parviz
    Senter, Leigha
    Eisen, Andrea
    Sun, Ping
    Narod, Steven A.
    OBESITY, 2012, 20 (06) : 1288 - 1292
  • [32] Assessment of ovarian reserve and reproductive outcomes in BRCA1 or BRCA2 mutation carriers
    Ponce, Jordi
    Fernandez-Gonzalez, Sergi
    Calvo, Iris
    Climent, Maite
    Penafiel, Judith
    Feliubadalo, Lidia
    Teule, Alex
    Lazaro, Conxi
    Maria Brunet, Joan
    Candas-Estebanez, Beatriz
    Retamal, Montserrat Duran
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2020, 30 (01) : 83 - 88
  • [33] Prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers
    Rebbeck, TR
    EUROPEAN JOURNAL OF CANCER, 2002, 38 : S15 - S17
  • [34] Prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers
    Rebbeck, TR
    JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (21) : 100S - 103S
  • [35] The Clinical Management of BRCA1 and BRCA2 Mutation Carriers
    Gulati, Anthony P.
    Domchek, Susan M.
    CURRENT ONCOLOGY REPORTS, 2008, 10 (01) : 47 - 53
  • [36] Cardiovascular Concerns in BRCA1 and BRCA2 Mutation Carriers
    Gast K.C.
    Viscuse P.V.
    Nowsheen S.
    Haddad T.C.
    Mutter R.W.
    Wahner Hendrickson A.E.
    Couch F.J.
    Ruddy K.J.
    Current Treatment Options in Cardiovascular Medicine, 2018, 20 (2)
  • [37] Clinical management of BRCA1 and BRCA2 mutation carriers
    Domchek, S. M.
    Weber, B. L.
    ONCOGENE, 2006, 25 (43) : 5825 - 5831
  • [38] Chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers
    Baeyens, A
    Thierens, H
    Claes, K
    Poppe, B
    De Ridder, L
    Vral, A
    INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2004, 80 (10) : 745 - 756
  • [39] The clinical management of BRCA1 and BRCA2 mutation carriers
    Anthony P. Gulati
    Susan M. Domchek
    Current Oncology Reports, 2008, 10 : 47 - 53
  • [40] Clinical management of BRCA1 and BRCA2 mutation carriers
    S M Domchek
    B L Weber
    Oncogene, 2006, 25 : 5825 - 5831