Tumor suppressor IKZF1 mediates glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia

被引：53
|
作者：
Marke, R. [1 ]
Havinga, J. [1 ]
Cloos, J. [2 ,3 ]
Demkes, M. [1 ]
Poelmans, G. [4 ,5 ,6 ,7 ]
Yuniati, L. [1 ]
Schenau, D. van Ingen [1 ]
Sonneveld, E. [8 ]
Waanders, E. [4 ,5 ]
Pieters, R. [9 ]
Kuiper, R. P. [4 ,5 ]
Hoogerbrugge, P. M. [9 ]
Kaspers, G. J. L. [2 ]
van Leeuwen, F. N. [1 ]
Scheijen, B. [1 ]
机构：
[1] Radboud Univ Nijmegen, Med Ctr, Lab Pediat Oncol, Nijmegen, Netherlands
[2] VU Univ Med, Dept Pediat Oncol Hematol, Amsterdam, Netherlands
[3] VU Univ Med, Dept Hematol, Amsterdam, Netherlands
[4] Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, Nijmegen, Netherlands
[5] Radboud Inst Mol Life Sci, Nijmegen, Netherlands
[6] Radboud Univ Nijmegen, Dept Cognit Neurosci, Nijmegen, Netherlands
[7] Radboud Univ Nijmegen, Dept Mol Anim Physiol, Nijmegen, Netherlands
[8] Dutch Childhood Oncol Grp, The Hague, Netherlands
[9] Princess Maxima Ctr Pediat Oncol, Utrecht, Netherlands
来源：
LEUKEMIA | 2016年 / 30卷 / 07期
关键词：
INHIBITION; DELETIONS; REVERSAL;
D O I：
10.1038/leu.2015.359
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：1599 / 1603
页数：6
相关论文
共 50 条
  • [31] High frequency of IKZF1 genetic alterations in adult patients with B-cell acute lymphoblastic leukemia
    Tokunaga, Kenji
    Yamaguchi, Shunichiro
    Iwanaga, Eisaku
    Nanri, Tomoko
    Shimomura, Taizo
    Suzushima, Hitoshi
    Mitsuya, Hiroaki
    Asou, Norio
    EUROPEAN JOURNAL OF HAEMATOLOGY, 2013, 91 (03) : 201 - 208
  • [32] Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients
    Scheijen, Blanca
    Boer, Judith M.
    Marke, Rene
    Tijchon, Esther
    Schenau, Dorette van Ingen
    Waanders, Esme
    van Emst, Liesbeth
    van der Meer, Laurens T.
    Pieters, Rob
    Escherich, Gabriele
    Horstmann, Martin A.
    Sonneveld, Edwin
    Venn, Nicola
    Sutton, Rosemary
    Dalla-Pozza, Luciano
    Kuiper, Roland P.
    Hoogerbrugge, Peter M.
    den Boer, Monique L.
    van Leeuwen, Frank N.
    HAEMATOLOGICA, 2017, 102 (03) : 541 - 551
  • [33] The Genomic Landscape of PAX5, IKZF1, and CDKN2A/B Alterations in B-Cell Precursor Acute Lymphoblastic Leukemia
    Ou, Zhishuo
    Sherer, Maureen
    Casey, Jane
    Bakos, Heather A.
    Vitullo, Kathleen
    Hu, Jie
    Friehling, Erika
    Gollin, Susanne M.
    Surti, Urvashi
    Yatsenko, Svetlana A.
    CYTOGENETIC AND GENOME RESEARCH, 2016, 150 (3-4) : 242 - 252
  • [34] Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia
    Tamai, Minori
    Kasai, Shin
    Akahane, Koshi
    Thu, Thao Nguyen
    Kagami, Keiko
    Komatsu, Chiaki
    Abe, Masako
    Watanabe, Atsushi
    Goi, Kumiko
    Miyake, Kunio
    Inaba, Toshiya
    Takita, Junko
    Goto, Hiroaki
    Minegishi, Masayoshi
    Iwamoto, Shotaro
    Sugita, Kanji
    Inukai, Takeshi
    JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2022, 218
  • [35] Poor Prognosis for IKZF1 Intra-Gene Deletions in Pediatric Ph- B-Cell Precursor Acute Lymphoblastic Leukemia
    Palmi, Chiara
    Silvestri, Daniela
    Longinotti, Giulia
    Vendramini, Elena
    Conter, Valentino
    Basso, Giuseppe
    Biondi, Andrea
    Valsecchi, Maria Grazia
    Kronnie, Geertruy Te
    Cazzaniga, Giovanni
    BLOOD, 2011, 118 (21) : 1500 - 1501
  • [36] Large deletions of the 5′ region of IKZF1 lead to haploinsufficiency in B-cell precursor acute lymphoblastic leukaemia
    Morel, Guillaume
    Deau, Marie-Celine
    Simand, Celestine
    Caye-Eude, Aurelie
    Arfeuille, Chloe
    Ittel, Antoine
    Miguet, Laurent
    Mauvieux, Laurent
    Herbrecht, Raoul
    Paillard, Catherine
    Strullu, Marion
    Cave, Helene
    Chan, Susan
    Kastner, Philippe
    Heizmann, Beate
    BRITISH JOURNAL OF HAEMATOLOGY, 2019, 186 (05) : E155 - E159
  • [37] The recombinome of IKZF1 deletions in B-cell precursor ALL
    Bruno A. Lopes
    Claus Meyer
    Heloysa Bouzada
    Marius Külp
    Ana Luiza Tardem Maciel
    Patrizia Larghero
    Thayana C. Barbosa
    Caroline P. Poubel
    Caroline Barbieri
    Nicola C. Venn
    Luciano Dalla Pozza
    Draga Barbaric
    Chiara Palmi
    Grazia Fazio
    Claudia Saitta
    Thais F. Aguiar
    Mecneide M. Lins
    Maura R. V. Ikoma-Colturato
    Marcia Schramm
    Eduardo Chapchap
    Gianni Cazzaniga
    Rosemary Sutton
    Rolf Marschalek
    Mariana Emerenciano
    Leukemia, 2023, 37 : 1727 - 1731
  • [38] Cuplike Nuclear Morphology in Pediatric B-cell Acute Lymphoblastic Leukemia is Highly Associated with IKZF1 Deletion
    Li, Weijie
    Cooley, Linda
    August, Keith
    Richardson, Aida
    MODERN PATHOLOGY, 2019, 32
  • [39] IKZF1 Deletions as a Prognostic Factor in Costa Rican Patients With Pediatric B-Cell Acute Lymphoblastic Leukemia
    Granados-Zamora, Melissa
    Chaves-Herrera, Karla
    Morera-Araya, Estela
    Granados-Alfaro, Paola
    Valverde-Munoz, Kathia
    Soto-Herrera, Gabriela
    Santamaria-Quesada, Carlos
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2020, 42 (06) : E401 - E406
  • [40] Allogeneic HCT for Adults with B-Cell Precursor Acute Lymphoblastic Leukemia Harboring IKZF1 Gene Mutations. A Study by the Acute Leukemia Working Party of the EBMT
    Giebel, Sebastian
    Labopin, Myriam
    Socie, Gerard
    Yakoub-Agha, Ibrahim
    Klein, Stefan
    Wagner-Drouet, Eva Maria
    Blaise, Didier
    Nguyen-Quoc, Stephanie
    Bourhis, Jean Henri
    Thiebaut, Anne
    Labussiere-Wallet, Helene
    Charbonnier, Amandine
    Berceanu, Ana
    Diez-Martin, J. L.
    Fegueux, Nathalie
    Esteve, Jordi
    Nagler, Arnon
    Mohty, Mohamad
    BONE MARROW TRANSPLANTATION, 2020, 55 (SUPPL 1) : 26 - 27
12345