A novel multi-component approach to the synthesis of pyrrolo[2,1-a]isoquinoline derivatives

被引:25
|
作者
Voskressensky, L. G. [1 ]
Borisova, T. N. [1 ]
Matveeva, M. D. [1 ]
Khrustalev, V. N. [1 ]
Aksenov, A. V. [2 ]
Titov, A. A. [1 ]
Vartanova, A. E. [1 ]
Varlamov, A. V. [1 ]
机构
[1] Peoples Friendship Univ Russia RUDN Univ, Dept Organ Chem, Miklukho Maklaya St 6, Moscow 117198, Russia
[2] North Caucasus Fed Univ, Dept Chem, 1 Pushkin St, Stavropol 355009, Russia
来源
RSC ADVANCES | 2016年 / 6卷 / 78期
基金
俄罗斯基础研究基金会;
关键词
PORTULACA-OLERACEA; TRIMETHYL ETHER; CARDUUS-CRISPUS; LAMELLARINS; ALKALOIDS; ISOQUINOLINE; FACILE;
D O I
10.1039/c6ra15810b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A route towards pyrrolo[2,1-a]isoquinolines through a 3CR of 1-aroyl dihydroisoquinolines, activated alkynes and alcohols has been developed.
引用
收藏
页码:74068 / 74071
页数:4
相关论文
共 50 条
  • [41] Cascade [3+2]/[4+2] Cycloaddition of Enaminones with Vinylene Carbonate for the Synthesis of Functionalized Pyrrolo[2,1-a]isoquinoline Derivatives
    Ma, Jian-Bo
    Zhao, Qing-Sheng
    Yin, Yi-Mai
    Yang, Shu
    Shao, Jia-Qi
    Yan, Sheng-Jiao
    ORGANIC LETTERS, 2024, 26 (45) : 9752 - 9758
  • [42] A synthesis of pyrrolo[2,1-a]isoquinolines through the reaction of activated acetylenes and isoquinoline in the presence of ethyl bromopyruvate
    Yavari, Issa
    Hossaini, Zinatossadat
    Sabbaghan, Maryam
    TETRAHEDRON LETTERS, 2006, 47 (34) : 6037 - 6040
  • [43] Pyrrolo[2,1-a]isoquinoline scaffolds for developing anti-cancer agents
    Garcia Maza, Leidy J.
    Salgado, Arturo Mendoza
    Kouznetsov, Vladimir V.
    Melendez, Carlos M.
    RSC ADVANCES, 2024, 14 (03) : 1710 - 1728
  • [44] Synthesis of Naphthoquinone- and Pyrrolo[2,1-a]isoquinoline-Fused Heterocycles and Tridemethoxy Lamellarin D
    Jhang, Jia-Wei
    Manjappa, Kiran B.
    Yang, Ding-Yah
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2022, 11 (01)
  • [45] Generation of Pyrrolo[2,1-a]isoquinoline Derivatives from N-ylides: Synthetic Control and Structural Characterization
    Dumitrascu, Florea
    Caira, Mino R.
    Georgescu, Emilian
    Georgescu, Florentina
    Draghici, Constantin
    Popa, Marcel Mirel
    HETEROATOM CHEMISTRY, 2011, 22 (06) : 723 - 729
  • [46] Synthesis of Benzimidazo[2,1-a]isoquinoline and Indolo[2,1-a]isoquinoline Derivatives via Copper-Catalyzed Silylation/Methylation of 2-Arylindoles and 2-Arylbenzimidazoles
    Zhao, Pengbo
    Wang, Youzhi
    Wang, Xiajun
    Zhuang, Daijiao
    Yan, Rulong
    JOURNAL OF ORGANIC CHEMISTRY, 2022, 87 (14): : 9056 - 9068
  • [47] Recent progress in the synthesis of pyrrolo[2,1-a]isoquinolines
    Cui, Hai-Lei
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2022, 20 (14) : 2779 - 2801
  • [48] The synthesis of indolo- and pyrrolo[2,1-a]isoquinolines
    de Koning, CB
    Michael, JP
    Pathak, R
    van Otterlo, WAL
    TETRAHEDRON LETTERS, 2004, 45 (06) : 1117 - 1119
  • [49] I2-DMSO Mediated Multicomponent [3+2] Annulation Reaction: An Approach to Pyrrolo[2,1-a]isoquinoline Derivatives with a Quaternary Center
    Zhuang, Shi-Yi
    Liu, Jin-Yi
    Guo, Hui
    Tang, Yong-Xing
    Chen, Xiang-Long
    Ma, Jin-Tian
    Wu, Yan-Dong
    Wu, An-Xin
    Zheng, Kai-Lu
    ORGANIC LETTERS, 2022, 24 (46) : 8573 - 8577
  • [50] Cyclopropenones in the synthesis of indolizidine, pyrrolo[2,1-a] isoquinoline and indolizino[8,7-b]indole alkaloids
    Jamshaid, Faisal
    Kondakal, Vishnu V. R.
    Newman, C. Declan
    Dobson, Rhianne
    Joao, Heidi
    Rice, Craig R.
    Mwansa, Joseph M.
    Thapa, Bimod
    Hemming, Karl
    TETRAHEDRON, 2020, 76 (45)