Rhodium(III)-Catalyzed Arylation of Boc-Imines via C-H Bond Functionalization

被引：263
|
作者：
Tsai, Andy S. [2 ]
Tauchert, Michael E. [3 ]
Bergman, Robert G. [1 ]
Ellman, Jonathan A. [2 ]
机构：
[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Chem Sci, Berkeley, CA 94720 USA
[2] Yale Univ, Dept Chem, New Haven, CT 06520 USA
[3] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 05期
关键词：
FRIEDEL-CRAFTS ALKYLATION; CARBON-CARBON BOND; ACTIVATION; CLEAVAGE; RH; HYDROARYLATION; ALKYNYLATION; ALDIMINES; ALDEHYDES; INSERTION;
D O I：
10.1021/ja109562x
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first rhodium-catalyzed arylation of imines proceeding via C-H bond functionalization is reported. Use of a non-coordinating halide abstractor is important to obtain reactivity. Aryl-branched N-Boc-amines are formed, and a wide range of functionality is compatible with the reaction.
引用
收藏
页码：1248 / 1250
页数：3
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