Synthesis of Selenyl-Substituted Quinoline Derivatives via Substrate-Controlled Three-Component Domino Reactions

被引：8

作者：

Sun, Shuang-Shuang ^{[1
]}

Mo, Zu-Yu ^{[1
]}

Chen, Yan-Yan ^{[1
]}

Xu, Yan-Li ^{[1
]}

机构：

[1] Guilin Med Univ, Pharm Sch, Guilin 541004, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 87卷 / 18期

关键词：

CASCADE REACTION; SELENOCYANATION; ACCESS;

D O I：

10.1021/acs.joc.2c01260

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient method for the preparation of selenyl-substituted quinoline derivatives through a C-Sp3-H selenylation of in situ-generated 3-acetyl quinoline has been developed. This protocol is easy to handle, scalable, and good functional group tolerant, providing a rapid method to 3-selenoacetyl quinoline and 3diselenoacetyl quinoline derivatives.

引用

页码：12447 / 12454

页数：8

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