Application of genetic algorithm in modelling and optimization of cellulase production

被引:25
|
作者
Sirohi, Ranjna [1 ]
Singh, Anupama [1 ]
Tarafdar, Ayon [1 ]
Shahi, N. C. [1 ]
机构
[1] GB Pant Univ Agr & Technol, Dept Postharvest Proc & Food Engn, Coll Technol, Pantnagar 263145, Uttarakhand, India
关键词
Cellulase; Genetic algorithm; Pea hull; Waste utilization; SOLID-STATE FERMENTATION; GLUCOAMYLASE; STRATEGIES; CORN;
D O I
10.1016/j.biortech.2018.09.105
中图分类号
S2 [农业工程];
学科分类号
0828 ;
摘要
The aim of this work was to study the application of genetic algorithm (GA) in modelling and optimization of cellulose production by Trichoderma reesei from pea hull. Enzyme activity of cellulase was determined using Filter Paper Activity (FPA) assay. Optimization of process parameters was performed using mathematical (MO) and genetic optimizers to obtain combination of variables for highest possible enzyme activity. GA generated a higher value of cellulase activity (0.353 U/mL) as compared to MO (0.302 U/mL). The values of independent variables in set (GA, MO) were: agitation speed (127, 120 rpm), % H2O2 concentration (10.36, 5.0), cultivation time (112, 91 h). The investigation highlights that GA could be used as a potential optimizer for processes involving waste utilization.
引用
收藏
页码:751 / 754
页数:4
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