Small Cell Transformation of Metastatic Prostate Adenocarcinoma Diagnosed by Dual-Tracer PET/CT (68Ga-PSMA and 18F-FDG): Potential Clinical Utility in Therapeutic Decision Making and Treatment Monitoring

被引：12
|
作者：
Parghane, Rahul
Basu, Sandip [1 ]
机构：
[1] Tata Mem Hosp Annexe, Radiat Med Ctr, Jerbai Wadia Rd, Mumbai 400012, Maharashtra, India
来源：
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY | 2019年 / 47卷 / 01期
关键词：
oncology; Lu-177-PSMA therapy; F-18-FDG PET/CT; Ga-68-PSMA PET/CT; penile metastases; small cell carcinoma of prostate;
D O I：
10.2967/jnmt.118.215582
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Transformed small cell carcinoma of the prostate represents a tumor biology distinct from its adenocarcinoma counterpart, and penile metastasis from prostate cancer is a rare phenomenon. Biologic heterogeneity among metastatic lesions in a patient with prostatic adenocarcinoma with SCPCa transformation is presented here. The case report shows the significance of using dual-tracer PET/CT with Ga-68-prostate-specific membrane antigen and F-18-FDG in diagnosing small cell carcinoma of prostate transformation in certain lesions, thereby guiding therapeutic strategies. Furthermore, the value of sequential dual-tracer PET/CT in assessing overall disease status, theranostics, and response to multimodality therapy is illustrated.
引用
收藏
页码：85 / 87
页数：3
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