Studies on some N-bridged heterocycles derived from bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes

被引：0

作者：

Holla, BS ^{[1
]}

Gonsalves, R

Shenoy, S

机构：

[1] Mangalore Univ, Dept Postgrad Studies & Res Chem, Mangalagangothri 574199, India

[2] KMC, Dept Microbiol, Mangalore 575001, India

来源：

FARMACO | 1998年 / 53卷 / 8-9期

关键词：

N-bridged heterocycles; bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes; antibacterial properties;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A series of bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes have been synthesized and were converted into bis-[1,2,4-triazolo[3,4-b]-1,3,4-thiadiazol-4-yl] alkanes. The newly synthesized compounds were characterized by analytical IR, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial properties and exhibited activity with MIC in the range 3-12.5 mu g/ml. (C) 1998 Elsevier Science S.A. All rights reserved.

引用

页码：574 / 578

页数：5

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