Low-Dose Quetiapine Causing Agranulocytosis and Leucopenia in a Patient with Benign Neutropenia: A Case Report
被引:2
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作者:
Fryer, Vincent
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机构:
Med Coll Wisconsin, Affiliated Hosp, Northeastern Wisconsin Psychiat Program, Green Bay, WI 54115 USAMed Coll Wisconsin, Affiliated Hosp, Northeastern Wisconsin Psychiat Program, Green Bay, WI 54115 USA
Fryer, Vincent
[1
]
Billings, James
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机构:
Med Coll Wisconsin, Affiliated Hosp, Northeastern Wisconsin Psychiat Program, Green Bay, WI 54115 USAMed Coll Wisconsin, Affiliated Hosp, Northeastern Wisconsin Psychiat Program, Green Bay, WI 54115 USA
Billings, James
[1
]
机构:
[1] Med Coll Wisconsin, Affiliated Hosp, Northeastern Wisconsin Psychiat Program, Green Bay, WI 54115 USA
Low white blood cell (WBC) counts and agranulocytosis are a relatively rare side effect of atypical antipsychotic treatment. Often, quetiapine is used as an adjunctive medication to help with sleep and mood in some patients. Many times, it is prescribed at lower doses when targeting this mechanism of action, especially when used in combination with antidepressants. The following case highlights the importance of understanding the potential risks in prescribing quetiapine in patients who have underlying genetic susceptibility towards low white blood cell counts.