Aluminium Oxide Thin-Film Based In Vitro Cell-Substrate Sensing Device for Monitoring Proliferation of Myoblast Cells

被引：4
|
作者：
Kasiviswanathan, Uvanesh [1 ]
Balavigneswaran, Chelladurai Karthikeyan [1 ]
Kumar, Chandan [2 ]
Poddar, Suruchi [1 ]
Jit, Satyabrata [2 ]
Sharma, Neeraj [1 ]
Mahto, Sanjeev Kumar [1 ]
机构：
[1] Banaras Hindu Univ, Sch Biomed Engn, Indian Inst Technol, Varanasi 221005, Uttar Pradesh, India
[2] Banaras Hindu Univ, Dept Elect Engn, Indian Inst Technol, Varanasi 221005, Uttar Pradesh, India
来源：
IEEE TRANSACTIONS ON NANOBIOSCIENCE | 2021年 / 20卷 / 03期
关键词：
Cells (biology); Monitoring; Substrates; Sensors; In vitro; Indium tin oxide; Aluminum oxide; Aluminium oxide; cell interaction; MIM structure; myoblast cells; mathematical modelling; DIELECTRIC-PROPERTIES; BIOSENSORS; MICRO; TIO2; BIOCOMPATIBILITY; NANOPARTICLES; FABRICATION; ADHESION; BEHAVIOR; DIOXIDE;
D O I：
10.1109/TNB.2021.3068318
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We demonstrate cell-substrate interaction on aluminium oxide thin-film in metal-insulator-metal structure followed by the change in dielectric characteristics of Al2O3 as a function of progression of cellular growth. The theoretical calculation of the fabricated biosensor reveals that the changes in the intrinsic elemental parameters are mainly attributed to the cell-induced behavioural changes.
引用
收藏
页码：331 / 337
页数：7
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