SYCAMORE - a systems biology computational analysis and modeling research environment

被引:24
|
作者
Weidemann, Andreas [1 ]
Richter, Stefan [2 ]
Stein, Matthias [2 ]
Sahle, Sven [1 ]
Gauges, Ralph [1 ]
Gabdoulline, Razif [2 ]
Surovtsova, Irina [1 ]
Semmelrock, Nils [2 ]
Besson, Bruno [2 ]
Rojas, Isabel
Wade, Rebecca [2 ]
Kummer, Ursula [1 ]
机构
[1] Heidelberg Univ, BIOQUANT, COS, Inst Zool,Dept Modeling Biol Proc, D-69120 Heidelberg, Germany
[2] EML Res, Mol & Cellular Modeling Grp, D-69118 Heidelberg, Germany
关键词
D O I
10.1093/bioinformatics/btn207
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
SYCAMORE is a browser-based application that facilitates construction, simulation and analysis of kinetic models in systems biology. Thus, it allows e.g. database supported modelling, basic model checking and the estimation of unknown kinetic parameters based on protein structures. In addition, it offers some guidance in order to allow non-expert users to perform basic computational modelling tasks.
引用
收藏
页码:1463 / 1464
页数:2
相关论文
共 50 条
  • [21] Computational systems biology
    Knudsen, TB
    REPRODUCTIVE TOXICOLOGY, 2004, 19 (01) : 1 - 2
  • [22] Computational systems biology
    Hiroaki Kitano
    Nature, 2002, 420 : 206 - 210
  • [23] Computational Systems Biology
    Zhao, Xing-Ming
    Tian, Weidong
    Jiang, Rui
    Wan, Jun
    SCIENTIFIC WORLD JOURNAL, 2013,
  • [24] Bioinformatics, computational biology and systems biology
    Wang M.D.
    IEEE Reviews in Biomedical Engineering, 2011, 4 : 3 - 5
  • [25] Hierarchical Modeling for Computational Biology
    Maus, Carsten
    John, Mathias
    Roehl, Mathias
    Uhrmacher, Adelinde M.
    FORMAL METHODS FOR COMPUTATIONAL SYSTEMS BIOLOGY, 2008, 5016 : 81 - 124
  • [26] Computational modeling of the EGF-receptor system: a paradigm for systems biology
    Wiley, HS
    Shvartsman, SY
    Lauffenburger, DA
    TRENDS IN CELL BIOLOGY, 2003, 13 (01) : 43 - 50
  • [27] Network inference, analysis, and modeling in systems biology
    Albert, Reke
    PLANT CELL, 2007, 19 (11): : 3327 - 3338
  • [28] FAIRDOMHub: a repository and collaboration environment for sharing systems biology research
    Wolstencroft, Katherine
    Krebs, Olga
    Snoep, Jacky L.
    Stanford, Natalie J.
    Bacall, Finn
    Golebiewski, Martin
    Kuzyakiv, Rostyk
    Quyen Nguyen
    Owen, Stuart
    Soiland-Reyes, Stian
    Straszewski, Jakub
    van Niekerk, David D.
    Williams, Alan R.
    Malmstrom, Lars
    Rinn, Bernd
    Mueller, Wolfgang
    Goble, Carole
    NUCLEIC ACIDS RESEARCH, 2017, 45 (D1) : D404 - D407
  • [29] MDScope:: A computational environment for structural biology
    Phillips, J
    Brunner, R
    Stone, J
    Kalé, L
    Skeel, R
    Schulten, K
    BIOPHYSICAL JOURNAL, 1999, 76 (01) : A245 - A245
  • [30] A conversation with ChatGPT on the role of computational systems biology in stem cell research
    Cahan, Patrick
    Treutlein, Barbara
    STEM CELL REPORTS, 2023, 18 (01): : 1 - 2