Synthesis and Antimicrobial Screening of Some Novel Pyrazoline Derivatives

被引：0
|
作者：
Kundariya, D. S. [1 ]
Rupala, R. G. [1 ]
Patel, P. K. [1 ]
机构：
[1] Maharaja Shree Mahendrasinhji Sci Coll, Dept Chem, Morbi 363642, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2012年 / 24卷 / 05期
关键词：
Chalcones; Pyrazolines; Antimicrobial activity; ANTIBACTERIAL;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new series of methyl-4-(4,5-dihydro-5-[(Z)phenyl]-1H-pyrazol-3-yl)-2-methylbenzohydrazide were synthesized by cyclisization of chalcones, methyl 4-((E)-3-((Z)phenyl)acryloyl)-2-methylbenzoate with hydrazine hydrate in presence of basic media. The chalcones were synthesized starting from 4-acetyl-2-methylbenzoic acid in 2 step. The structures of the synthesized compounds have been established on the basis of physical and spectral data and are screened for antimicrobial activity. Some of them exhibited significant activity.
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收藏
页码：2045 / 2048
页数：4
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