CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 (vol 413, pg 179, 2001)

被引：7
|
作者：
Herzig, S
Long, FX
Jhala, US
Hedrick, S
Quinn, R
Bauer, A
Rudolph, D
Schutz, G
Yoon, C
Puigserver, P
Spiegelman, B
Montminy, M
机构：
来源：
NATURE | 2001年 / 413卷 / 6856期
关键词：
D O I：
10.1038/35098123
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Nature, 413, 179–183 (2001). In the third sentence, “hyperglycaemia” should have read “hypoglycaemia”. The corrected sentence is: "Here we show that mice carrying a targeted disruption of the cyclic AMP (cAMP) response element binding (CREB) protein gene, or overexpressing a dominant-negative CREB inhibitor, exhibit fasting hypoglycaemia and reduced expression of gluconeogenic enzymes."
引用
收藏
页码：652 / 652
页数：1
相关论文
共 50 条
  • [31] Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1α
    Handschin, C
    Lin, JD
    Rhee, J
    Peyer, AK
    Chin, S
    Wu, PH
    Meyer, UA
    Spiegelman, BM
    CELL, 2005, 122 (04) : 505 - 515
  • [32] Circadian Metabolic Regulation through Crosstalk between Casein Kinase 1δ and Transcriptional Coactivator PGC-1α
    Li, Siming
    Chen, Xiao-Wei
    Yu, Lei
    Saltiel, Alan R.
    Lin, Jiandie D.
    MOLECULAR ENDOCRINOLOGY, 2011, 25 (12) : 2084 - 2093
  • [33] Modulation of PGC-1 Coactivator Pathways in Brown Fat Differentiation through LRP130
    Cooper, Marcus P.
    Uldry, Marc
    Kajimura, Shingo
    Arany, Zoltan
    Spiegelman, Bruce M.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (46) : 31960 - 31967
  • [34] miR-696 plays a role in hepatic gluconeogenesis in ob/ob mice by targeting PGC-1α
    Fang, Zhijuan
    Li, Peng
    Jia, Wenhui
    Jiang, Ting
    Wang, Zhongyun
    Xiang, Yang
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2016, 38 (03) : 845 - 852
  • [35] The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator
    Tavares, Clint D. J.
    Sharabi, Kfir
    Dominy, John E.
    Lee, Yoonjin
    Isasa, Marta
    Orozco, Jose M.
    Jedrychowski, Mark P.
    Kamenecka, Theodore M.
    Griffin, Patrick R.
    Gygi, Steven P.
    Puigserver, Pere
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (20) : 10635 - 10645
  • [36] The transcriptional coactivator PGC-1α regulates cardiac mitochondrial function and dictates the supply of ATP available for contractile reserve
    Arany, ZP
    He, HM
    Lin, JD
    Hoyer, K
    Schoen, FJ
    Ingwall, J
    Spiegelman, B
    CIRCULATION, 2005, 111 (13) : 1722 - 1722
  • [37] SUMO-specific Protease 1 Regulates Mitochondrial Biogenesis through PGC-1α
    Cai, Rong
    Yu, Tingting
    Huang, Chao
    Xia, Xuefeng
    Liu, Xiaobing
    Gu, Jianmin
    Xue, Song
    Yeh, Edward T. H.
    Cheng, Jinke
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (53) : 44464 - 44470
  • [38] Hepatic oleate regulates liver stress response partially through PGC-1α during high-carbohydrate feeding
    Liu, Xueqing
    Burhans, Maggie S.
    Flowers, Matthew T.
    Ntambi, James M.
    JOURNAL OF HEPATOLOGY, 2016, 65 (01) : 103 - 112
  • [39] Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic SIRT1/PGC-1 α pathway
    Meng, Decheng
    Yin, Guoliang
    Chen, Suwen
    Zhang, Xin
    Yu, Wenfei
    Wang, Linya
    Liu, Hongshuai
    Jiang, Wenying
    Sun, Yuqing
    Zhang, Fengxia
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2024, 977
  • [40] Propofol ameliorates acute postoperative fatigue and promotes glucagon-regulated hepatic gluconeogenesis by activating CREB/PGC-1α and accelerating fatty acids beta-oxidation
    Zhang, W. W.
    Xue, R.
    Mi, T. Y.
    Shen, X. M.
    Li, J. C.
    Li, S.
    Zhang, Y.
    Li, Y.
    Wang, L. X.
    Yin, X. L.
    Wang, H. L.
    Zhang, Y. Z.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 586 : 121 - 128
12345