New insight into calcinosis of juvenile dermatomyositis: A study of composition and treatment

被引:91
|
作者
Mukamel, M
Horev, G
Mimouni, M
机构
[1] Schneider Childrens Med Ctr Israel, Pediat Rheumatol Unit, IL-49202 Petah Tiqwa, Israel
[2] Schneider Childrens Med Ctr Israel, Pediat Imaging Dept, IL-49202 Petah Tiqwa, Israel
[3] Schneider Childrens Med Ctr Israel, Day Care Unit, IL-49202 Petah Tiqwa, Israel
[4] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel
来源
JOURNAL OF PEDIATRICS | 2001年 / 138卷 / 05期
关键词
D O I
10.1067/mpd.2001.112473
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Milk of calcium developed in 2 children with juvenile dermatomyositis. The fluid of the collection contained macrophages, interleukin-6, IL-I, and tumor necrosis factor. The patient who had dystrophic calcinosis had a dramatic improvement with the introduction of alendronate. These findings suggest that calcinosis of juvenile dermatomyositis may be mediated by activated macrophages and that alendronate can be an effective treatment for this condition.
引用
收藏
页码:763 / 766
页数:4
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