Synthesis of differently disubstituted 2,2′-bipyridines by a modified Negishi cross-coupling reaction

被引:38
|
作者
Lützen, A [1 ]
Hapke, M [1 ]
Staats, H [1 ]
Bunzen, J [1 ]
机构
[1] Carl von Ossietzky Univ Oldenburg, Dept Chem, D-26111 Oldenburg, Germany
关键词
biaryls; cross-coupling; Negishi reaction; 2,2 '-bipyridines;
D O I
10.1002/ejoc.200300192
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A general practical approach to a number of differently disubstituted 2,2'-bipyridines from substituted 2-bromo- and 2-chloropyridines by application of modified Negishi cross-coupling conditions has been developed. These 2,2'-bipyridines carry versatile functional groups that can be elaborated further, as demonstrated for some examples. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
引用
收藏
页码:3948 / 3957
页数:10
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