Noncontact Wide-Field Multispectral Imaging for Tissue Characterization

被引:5
|
作者
Kainerstorfer, Jana M. [1 ]
Smith, Paul D. [2 ]
Gandjbakhche, Amir H. [1 ]
机构
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Pediat Imaging & Tissue Sci, Sect Analyt & Funct Biophoton, NIH, Bethesda, MD 20892 USA
[2] Natl Inst Biomed Imaging & Bioengn, Lab Cellular Imaging & Macromol Biophys, Biomed Instrumentat & Multiscale Imaging Sect, NIH, Bethesda, MD 20892 USA
关键词
Biophotonics; multispectral imaging; optical imaging; wide-field imaging; NEAR-INFRARED SPECTROSCOPY; INDEPENDENT-COMPONENT ANALYSIS; PHASE-MEASURING PROFILOMETRY; SPATIAL-FREQUENCY-DOMAIN; HUMAN-SKIN INVIVO; POLARIZED-LIGHT; OPTICAL TOMOGRAPHY; TURBID MEDIA; LESION CLASSIFICATION; CUTANEOUS HEMOGLOBIN;
D O I
10.1109/JSTQE.2011.2175708
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Imaging of large tissue areas (>5 cm(2)) is often desired in clinical settings, e.g., of tissue oxygenation. Intrinsic contrasts such as absorption and scattering changes have the potential to enhance diagnostics and help monitor diseased tissue. An overview of existing noncontact multispectral diffuse reflectance imaging modalities for tissue characterization based on intrinsic optical contrast due to absorption and scattering properties of tissue is given here. Also, an overview of instrumentation advances, modeling approaches, applications, and ongoing work is described, primarily in, but not limited to, skin imaging, demonstrating the benefits and limitations of wide-field diffuse reflectance imaging.
引用
收藏
页码:1343 / 1354
页数:12
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