Reaction of 3-hydroxy-1,2,3,4-tetrahydroquinoline-2,4-diones with ethyl(triphenylphosphoranylidene) acetate

被引：18

作者：

Kafka, S ^{[1
]}

Kovar, M ^{[1
]}

Klasek, A ^{[1
]}

Kappe, T ^{[1
]}

机构：

[1] KARL FRANZENS UNIV GRAZ,INST ORGAN CHEM,A-8010 GRAZ,AUSTRIA

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1996年 / 33卷 / 06期

关键词：

D O I：

10.1002/jhet.5570330667

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Wittig reaction of 3-hydroxy-1,2,3,4-tetrahydroquinoline-2,4-diones 2 with ethyl (triphenylphosphoranylidene)acetate 3 proceeds stereoselectively to give E-4-carbethoxymethylene-1,2,3,4-tetrahydro-2-quinolones 4, which were hydrolyzed to corresponding acids 6. Butenolides 5 were detected end, in some cases, isolated as a minor product of the Wittig reaction.

引用

页码：1977 / 1982

页数：6

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