Materials as morphogenetic guides in tissue engineering

被引：268
|
作者：
Hubbell, JA [1 ]
机构：
[1] Ecole Polytech Fed Lausanne, Swiss Fed Inst Technol, Inst Biol & Chem Engn, CH-1015 Lausanne, Switzerland
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2003年 / 14卷 / 05期
关键词：
D O I：
10.1016/j.copbio.2003.09.004
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Within native tissues cells are held within the extracellular matrix (ECM), which has a role in maintaining homeostasis, guiding development and directing regeneration. Efforts in tissue engineering have aimed to mimick the ECM to help guide morphogenesis and tissue repair. Studies have not only looked at ways to mimick the structure and characteristics of the ECM, but have also considered ways to reproduce its molecular properties including its bioadhesive character, proteolytic susceptibility and ability to bind growth factors.
引用
收藏
页码：551 / 558
页数：8
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