Effect of off-resonance on T1 saturation recovery measurement in inhomogeneous fields

被引：8

作者：

Duan, Chong ^{[1
,2
]}

Ryan, Colm ^{[1
,3
]}

Utsuzawa, Shin ^{[1
]}

Song, Yi-Qiao ^{[1
]}

Hurlimann, Martin D. ^{[1
]}

机构：

[1] Schlumberger Doll Res Ctr, Cambridge, MA 02139 USA

[2] Washington Univ, Dept Chem, St Louis, MO 63110 USA

[3] Raytheon BBN Technol, Cambridge, MA 02138 USA

来源：

JOURNAL OF MAGNETIC RESONANCE | 2017年 / 281卷

关键词：

Saturation recovery; T-1; Off-resonance; Dynamic equilibrium;

D O I：

10.1016/j.jmr.2017.05.003

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Saturation-recovery measurements with Carr-Purcell-Meiboom-Gill sequences are commonly employed to measure the longitudinal relaxation time constant, T-1, in grossly inhomogeneous fields. We show that in general the off-resonant effect generates unexpected extra signals in the T-1 measurement. In the present study, we derive a modified T-1, kernel that accounts for this off-resonance effect quantitatively. The new kernel has been tested with numerical simulations and experiments, and excellent agreement is found. (C) 2017 Elsevier Inc. All rights reserved.

引用

页码：31 / 43

页数：13

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