Inhaled corticosteroid use for asthma is linked to adrenal suppression

被引:1
|
作者
Lasky-Su, Jessica [1 ,2 ]
机构
[1] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
[2] Harvard Med Sch, Boston, MA 02115 USA
关键词
D O I
10.1038/s41591-022-01732-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The largest metabolomic study of asthma thus far, comprising >14,000 people from four independent cohorts, has found that inhaled corticosteroid (ICS) treatment is associated with adrenal suppression, even at low doses. Thus, ICS dosage should be optimized to minimize adrenal suppression while maintaining its established benefits in asthma management.
引用
收藏
页码:645 / 646
页数:2
相关论文
共 50 条
  • [21] USE OF SPACERS TO FACILITATE INHALED CORTICOSTEROID TREATMENT OF ASTHMA
    TOOGOOD, JH
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1985, 131 (02): : 301 - 301
  • [22] Inhaled corticosteroid use in asthma and the prevention of myocardial infarction
    Suissa, S
    Assimes, T
    Brassard, P
    Ernst, P
    AMERICAN JOURNAL OF MEDICINE, 2003, 115 (05): : 377 - 381
  • [23] Dynamics of inhaled corticosteroid use are associated with asthma attacks
    Lee, Joy
    Huvanandana, Jacqueline
    Foster, Juliet M.
    Reddel, Helen K.
    Abramson, Michael J.
    Thamrin, Cindy
    Hew, Mark
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [24] USE OF SPACERS TO FACILITATE INHALED CORTICOSTEROID TREATMENT OF ASTHMA
    TOOGOOD, JH
    BASKERVILLE, J
    JENNINGS, B
    LEFCOE, NM
    JOHANSSON, SA
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1984, 129 (05): : 723 - 729
  • [25] USE OF SPACERS TO FACILITATE INHALED CORTICOSTEROID TREATMENT OF ASTHMA
    NEWHOUSE, MT
    DOLOVICH, M
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1984, 130 (05): : 951 - 951
  • [26] Inhaled corticosteroid related adrenal suppression detected by poor growth and reversed with ciclesonide
    Liddell, Brian S.
    Oberlin, John M.
    Hsu, Daniel P.
    JOURNAL OF ASTHMA, 2017, 54 (01) : 99 - 104
  • [27] Inhaled Corticosteroid Related Adrenal Suppression Detected by Poor Growth and Reversed by Ciclesonide
    Liddell, Brian S.
    Oberlin, John
    Hsu, Daniel
    PEDIATRICS, 2018, 141
  • [28] Cushing syndrome, adrenal suppression and local corticosteroid use
    Hameed, Rubina
    Zacharin, Margaret R.
    JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 2006, 42 (06) : 392 - 394
  • [29] INHALED CORTICOSTEROID TREATMENT FOR ASTHMA
    LAITINEN, LA
    LAITINEN, A
    ALLERGY PROCEEDINGS, 1995, 16 (02): : 63 - 66
  • [30] Inhaled corticosteroid dosage in asthma
    Reddel, HK
    Marks, GB
    Salome, CM
    Jenkins, CR
    THORAX, 2002, 57 (09) : 837 - 838