TARGETING HISTONE MUTATIONS IN PEDIATRIC HIGH GRADE GLIOMAS

被引:0
|
作者
Daniels, David [1 ]
Zhang, Zhiguo [1 ]
Rao, Amulya Nageswara [1 ]
机构
[1] Mayo Clin, Rochester, MN USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
HG-15
引用
收藏
页码:50 / 51
页数:2
相关论文
共 50 条
  • [21] Hypermutant Pediatric High Grade Gliomas are Driven by RAS/MAPK Mutations and Respond to MEK Inhibition
    Campbell, B.
    Morgenstern, D.
    Lipman, T.
    Fabrizio, D.
    Bouffet, E.
    Hawkins, C.
    Tabori, U.
    PEDIATRIC BLOOD & CANCER, 2018, 65 : S68 - S68
  • [22] HYPERMUTANT PEDIATRIC HIGH GRADE GLIOMAS ARE DRIVEN BY RAS/MAPK MUTATIONS AND RESPOND TO MEK INHIBITION
    Campbell, Brittany B.
    Morgenstern, Daniel A.
    Lipman, Tatiana
    Fabrizio, David
    Shlien, Adam
    Bouffet, Eric
    Hawkins, Cynthia
    Tabori, Uri
    NEURO-ONCOLOGY, 2018, 20 : 66 - 66
  • [23] Modeling the Landscape of Histone-Mutant Pediatric High-Grade Gliomas: A Study in Partner Alterations
    Lubanszky, Evan
    Hawkins, Cynthia
    CANCER DISCOVERY, 2023, 13 (07) : 1516 - 1517
  • [24] Differentiation therapy targeting the stalled epigenetic developmental programs in pediatric high-grade gliomas
    Xiang, Wang
    Zhang, Xiaolin
    Dong, Minhai
    Wan, Lijun
    Zhang, Bin
    Wan, Feng
    PHARMACOLOGICAL RESEARCH, 2025, 212
  • [25] Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas
    Shen, Han
    Yu, Man
    Tsoli, Maria
    Chang, Cecilia
    Joshi, Swapna
    Liu, Jie
    Ryall, Scott
    Chornenkyy, Yevgen
    Siddaway, Robert
    Hawkins, Cynthia
    Ziegler, David S.
    NEURO-ONCOLOGY, 2020, 22 (01) : 139 - 151
  • [26] Pediatric High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas
    Fangusaro, Jason
    JOURNAL OF CHILD NEUROLOGY, 2009, 24 (11) : 1409 - 1417
  • [27] PRIMARY CELL LINES OF PEDIATRIC HIGH GRADE GLIOMAS (PHGGS) WITH HISTONE H3.3 MUTATIONS ARE MIMICKING INTER AND INTRA-TUMOR HETEROGENEITY
    Blandin, Anne-Florence
    Durand, Aurelie
    Litzler, Marie
    Guerin, Eric
    Tripp, Aurelien
    Lelong-Rebel, Isabelle
    Dontenwill, Monique
    Jacques Namer, Izzie
    Guenot, Dominique
    Entz-Werle, Natacha
    NEURO-ONCOLOGY, 2017, 19 : 49 - 49
  • [28] Role of histone H3 in high grade gliomas
    Mancebo, X. Ara
    Fuentes-Camps, E. M.
    Alborch-Gil, C.
    Cajal, S. Ramon Y.
    Martinez-Saez, E.
    VIRCHOWS ARCHIV, 2020, 477 : S214 - S214
  • [29] Cerebellar high-grade gliomas do not present the same molecular alterations as supratentorial high-grade gliomas and may show histone H3 gene mutations
    Tauziede-Espariat, Arnault
    Saffroy, Raphael
    Pages, Melanie
    Pallud, Johan
    Legrand, Laurence
    Besnard, Aurore
    Lacombe, Joelle
    Lot, Guillaume
    Borha, Alin
    Tazi, Sanaa
    Adle-Biassette, Homa
    Polivka, Marc
    Lechapt, Emmanuele
    Varlet, Pascale
    CLINICAL NEUROPATHOLOGY, 2018, 37 (05) : 209 - 216
  • [30] Epigenetic addiction in pediatric high-grade gliomas
    Jabado, Nada
    CANCER RESEARCH, 2015, 75