A silencer located 3′ to the Aγ-globin gene influences the transcription of the human β-globin locus at the embryonic yolk sac stage in transgenic mice.

被引：0
|
作者：
Katsantoni, E
de Krom, M
Imam, A
Kong-a-San, J
Grosveld, F
Anagnou, NP
Strouboulis, J
机构：
[1] Univ Crete, Sch Med, Dept Basic Sci, Iraklion, Greece
[2] Inst Mol Biol & Biotechnol, Iraklion, Greece
[3] Erasmus Univ, Fac Med, Dept Cell Biol & Genet, NL-3000 DR Rotterdam, Netherlands
[4] Erasmus Univ, Fac Med, Ctr Biomed Genet, NL-3000 DR Rotterdam, Netherlands
[5] Univ Athens, Sch Med, Dept Basic Sci, GR-11527 Athens, Greece
来源：
BLOOD CELLS MOLECULES AND DISEASES | 2003年 / 31卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：148 / 149
页数：2
相关论文
共 50 条
  • [21] HUMAN GAMMA-GLOBIN TO BETA-GLOBIN GENE SWITCHING IN TRANSGENIC MICE
    BEHRINGER, RR
    RYAN, TM
    PALMITER, RD
    BRINSTER, RL
    TOWNES, TM
    GENES & DEVELOPMENT, 1990, 4 (03) : 380 - 389
  • [22] The αHS-40 enhancer fails to activate human γ-globin gene expression in transgenic mice.
    Li, QL
    Han, HM
    Ye, X
    Stafford, M
    Emery, DW
    Stamatoyannopoulos, G
    BLOOD, 2003, 102 (11) : 35B - 36B
  • [23] Chromatin structure and transcription of the globin locus in HS1-4 knockout mice.
    Pawlik, KM
    Townes, TM
    BLOOD CELLS MOLECULES AND DISEASES, 2000, 26 (05) : 524 - 524
  • [24] Chicken β-globin HS4 insulator functions in a retrovirus silencer-blocking assay in transgenic mice.
    Osborne, CS
    Pasceri, P
    Sukonnik, T
    Yao, S
    Ellis, J
    BLOOD CELLS MOLECULES AND DISEASES, 2000, 26 (05) : 523 - 523
  • [25] Expression of human α-like globin genes in BAC-mediated transgenic mice.
    Feng, DX
    Liu, DP
    Huang, Y
    Wu, L
    Li, TC
    Wu, M
    Liang, CC
    BLOOD CELLS MOLECULES AND DISEASES, 2000, 26 (05) : 520 - 520
  • [26] Studying the developmental regulation of the human beta-globin locus in transgenic mice
    Clegg, CH
    Haugen, HS
    Stamatoyannopoulos, G
    Peterson, KR
    LAB ANIMAL, 1997, 26 (08) : 43 - +
  • [27] A 5' CONTROL REGION OF THE HUMAN EPSILON-GLOBIN GENE IS SUFFICIENT FOR EMBRYONIC SPECIFICITY IN TRANSGENIC MICE
    SHIH, DM
    WALL, RJ
    SHAPIRO, SG
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (05) : 3066 - 3071
  • [28] Gene expression in somatic cell hybrids derived from embryonic mice transgenic for human globin genes
    Stanworth, SJ
    Roberts, NA
    Sharpe, JA
    Wood, WG
    BRITISH JOURNAL OF HAEMATOLOGY, 1996, 94 (04) : 631 - 638
  • [29] The Aγ-globin 3′ element provides no unique function(s) for human β-globin locus gene regulation
    Liu, QH
    Tanimoto, K
    Bungert, J
    Engel, JD
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (17) : 9944 - 9949
  • [30] The human Band 3 (AE 1) promoter linked to the human Aγ-globin gene demonstrates erythroid specific but variegated expression in transgenic mice.
    Frazar, TF
    Anderson, SM
    Cline, AP
    Garrett, LJ
    Gallagher, PG
    Bodine, DM
    BLOOD, 2000, 96 (11) : 132B - 132B
12345