Giant Fold Gastritis Induced by Epoprostenol Infusion in Patients With Pulmonary Arterial Hypertension

被引:3
|
作者
Miura, Yohei [1 ]
Kataoka, Masaharu [3 ]
Chiba, Tomohiro [2 ]
Inami, Takumi [1 ]
Yoshino, Hideaki [1 ]
Satoh, Toru [1 ]
机构
[1] Kyorin Univ, Sch Med, Dept Internal Med 2, Div Cardiol, Tokyo, Japan
[2] Kyorin Univ, Sch Med, Dept Pathol, Tokyo, Japan
[3] Keio Univ, Sch Med, Dept Cardiol, Tokyo, Japan
关键词
Epoprostenol; Giant fold gastritis; Pulmonary arterial hypertension; Stomach barium examination; THERAPY;
D O I
10.1253/circj.CJ-18-0349
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Epoprostenol infusion is the strongest and most convincing therapeutic strategy for severe pulmonary arterial hypertension (PAH). This study investigated the gastrointestinal side effects of epoprostenol. Methods and Results: The study group of 12 patients treated with epoprostenol (epoprostenol group) and 4 patients without epoprostenol (control group) underwent stomach barium examination, which revealed that the prevalence of giant fold gastritis was significantly higher in the patients treated with epoprostenol (75% in epoprostenol group vs. 0% in control group; P=0.019). Conclusions: Giant fold gastritis may be an important side effect of epoprostenol infusion.
引用
收藏
页码:2676 / 2677
页数:2
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