One-Pot Synthesis of Benzo[4,5]imidazo[1,2-a]pyrimidine Derivatives Using Melamine Trisulfonic Acid as Catalyst

被引：0
|
作者：
Shang, Xiaojun [1 ]
Geng, Mingjiang [2 ]
Wu, Liqiang [1 ]
机构：
[1] Xinxiang Med Univ, Sch Pharm, Xinxiang 453003, Henan Province, Peoples R China
[2] Xinxiang Med Univ, Dept Chem, Xinxiang 453003, Henan Province, Peoples R China
来源：
ASIAN JOURNAL OF CHEMISTRY | 2012年 / 24卷 / 02期
关键词：
Naphtho[1 ',2 ':5,6]pyrano[3,2-c]chromen-6-one; 4-Hydroxycoumarin; Alum; Solvent-free; RING-SYSTEMS; EFFICIENT; ALCOHOLS; MTSA;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Melamine trisulfonic acid catalyzes efficiently the one-pot condensation of 2-aminobenzimidazole, aldehyde and beta-dicarbonyl compounds under solvent-free conditions to afford the corresponding benzo[4,5]imidazo[1,2-a]pyrimidine derivatives in single step. This new approach consistently has the advantage of excellent yields (86-95 %) and short reaction times of 4-6 h. The catalyst can be recovered and recycle.
引用
收藏
页码：515 / 517
页数：3
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