One-Pot Synthesis of Benzo[4,5]imidazo[1,2-a]pyrimidine Derivatives Using Melamine Trisulfonic Acid as Catalyst

被引：0

作者：

Shang, Xiaojun ^{[1
]}

Geng, Mingjiang ^{[2
]}

Wu, Liqiang ^{[1
]}

机构：

[1] Xinxiang Med Univ, Sch Pharm, Xinxiang 453003, Henan Province, Peoples R China

[2] Xinxiang Med Univ, Dept Chem, Xinxiang 453003, Henan Province, Peoples R China

来源：

ASIAN JOURNAL OF CHEMISTRY | 2012年 / 24卷 / 02期

关键词：

Naphtho[1 ',2 ':5,6]pyrano[3,2-c]chromen-6-one; 4-Hydroxycoumarin; Alum; Solvent-free; RING-SYSTEMS; EFFICIENT; ALCOHOLS; MTSA;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Melamine trisulfonic acid catalyzes efficiently the one-pot condensation of 2-aminobenzimidazole, aldehyde and beta-dicarbonyl compounds under solvent-free conditions to afford the corresponding benzo[4,5]imidazo[1,2-a]pyrimidine derivatives in single step. This new approach consistently has the advantage of excellent yields (86-95 %) and short reaction times of 4-6 h. The catalyst can be recovered and recycle.

引用

页码：515 / 517

页数：3

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