Tissue transglutaminase inhibition

被引：10
|
作者：
Keillor, JW [1 ]
机构：
[1] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada
来源：
CHEMISTRY & BIOLOGY | 2005年 / 12卷 / 04期
关键词：
D O I：
10.1016/j.chembiol.2005.04.001
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Khosla and coworkers report the synthesis of peptidic dihydroisoxazole derivatives, the in vitro evaluation of these novel compounds as inhibitors of recombinant human tissue transglutaminase (TG2), and their oral bioavailability and efficacy for the synergistic treatment of glioblastoma tumors [1].
引用
收藏
页码：410 / 412
页数：3
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