Rapid Polymyxin NP test for the detection of polymyxin resistance mediated by the mcr-1/mcr-2 genes

被引：39
|
作者：
Poirel, Laurent [1 ,2 ,3 ,4 ]
Larpin, Yu [1 ,2 ,3 ]
Dobias, Jan [1 ]
Stephan, Roger [5 ]
Decousser, Jean-Winoc [6 ,7 ]
Madec, Jean-Yves [8 ]
Nordmann, Patrice [1 ,2 ,3 ,4 ,9 ,10 ]
机构：
[1] Univ Fribourg, Dept Med, Emerging Antibiot Resistance Med & Mol Microbiol, Fribourg, Switzerland
[2] IAME, INSERM, European Unit, Paris, France
[3] Univ Fribourg, INSERM, European Unit, Fribourg, Switzerland
[4] Univ Fribourg, Swiss Natl Reference Ctr Emerging Antibiot Resist, Fribourg, Switzerland
[5] Univ Zurich, Vetsuisse Fac, Inst Food Safety & Hyg, Zurich, Switzerland
[6] Univ Hosp Henri Mondor, AP HP, Dept Virol Bacteriol Infect Control, Parasitol Mycol, Creteil, France
[7] INSERM, UMR 1137, IAME, Paris, France
[8] Agence Natl Secur Sanit Anses, Unite Antibioresistance & Virulence Bacteriennes, Lyon, France
[9] Univ Lausanne, Inst Microbiol, Lausanne, Switzerland
[10] Univ Hosp Ctr, Lausanne, Switzerland
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2018年 / 90卷 / 01期
关键词：
Polymyxin; MCR; Resistance; Enterobacteriaceae; Rapid Polymyxin NP test; ESCHERICHIA-COLI;
D O I：
10.1016/j.diagmicrobio.2017.09.012
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The Rapid Polymyxin NP test has been recently developed to rapidly detect polymyxin resistance in Enterobacteriaceae. Here we evaluated this test for detecting MCR-1/MCR-2-producing Enterobacteriaceae using a collection of 70 non-redundant strains either recovered from the environment, animals, or humans. Sensitivity and specificity were found to be 100%. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码：7 / 10
页数：4
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