There are few reports of chemotherapy-induced eccrine squamous syringometaplasia in children. We report the first case of an infant developing this condition after treatment with busulfan, fludarabine, and antithymocyte globulin in preparation for bone marrow transplantation. Twenty-eight days after transplantation, the infant developed faintly erythematous papules and plaques on the bilateral axillae, inguinal folds, and sites of adhesives. Punch biopsy revealed eccrine glands with dyskeratotic cells and focal squamous metaplasia consistent with chemotherapy-induced eccrine squamous syringometaplasia.
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Plus Care Int Private Ltd, Dept Histopathol, Mumbai, Maharashtra, IndiaPlus Care Int Private Ltd, Dept Histopathol, Mumbai, Maharashtra, India
Patkar, Rakesh Rajiv
Mishra, Shilpa
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Plus Care Int Private Ltd, Dept Histopathol, Mumbai, Maharashtra, India
Top Floor,25 Firuz Ara,Opposite Cooperage Bandstan, Mumbai 400021, Maharashtra, IndiaPlus Care Int Private Ltd, Dept Histopathol, Mumbai, Maharashtra, India
Mishra, Shilpa
Neelakantan, Amrita
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Plus Care Int Private Ltd, Dept Histopathol, Mumbai, Maharashtra, IndiaPlus Care Int Private Ltd, Dept Histopathol, Mumbai, Maharashtra, India
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Univ Natal, Nelson R Mandela Med Sch, Sch Pathol & Lab Med, Dept Anat Pathol, ZA-4001 Durban, South AfricaUniv Natal, Nelson R Mandela Med Sch, Sch Pathol & Lab Med, Dept Anat Pathol, ZA-4001 Durban, South Africa
Chetty, R
Ramdial, PK
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Univ Natal, Nelson R Mandela Med Sch, Sch Pathol & Lab Med, Dept Anat Pathol, ZA-4001 Durban, South AfricaUniv Natal, Nelson R Mandela Med Sch, Sch Pathol & Lab Med, Dept Anat Pathol, ZA-4001 Durban, South Africa
Ramdial, PK
Govender, D
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Univ Natal, Nelson R Mandela Med Sch, Sch Pathol & Lab Med, Dept Anat Pathol, ZA-4001 Durban, South AfricaUniv Natal, Nelson R Mandela Med Sch, Sch Pathol & Lab Med, Dept Anat Pathol, ZA-4001 Durban, South Africa