Cebranopadol: a first in-class example of a nociceptin/orphanin FQ receptor and opioid receptor agonist

被引：41
|
作者：
Lambert, D. G. [1 ]
Bird, M. F. [1 ]
Rowbotham, D. J. [1 ]
机构：
[1] Univ Leicester, Leicester Royal Infirm, Dept Cardiovasc Sci, Div Anaesthesia Crit Care & Pain Management, Leicester LE2 7LX, Leics, England
来源：
BRITISH JOURNAL OF ANAESTHESIA | 2015年 / 114卷 / 03期
关键词：
KNOCK-OUT MICE; MORPHINE-TOLERANCE; DRUG-ABUSE; DEPENDENCE; NOP; PEPTIDE; TARGET;
D O I：
10.1093/bja/aeu332
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
引用
收藏
页码：364 / 366
页数：3
相关论文
共 50 条
  • [21] The orphan opioid receptor and its endogenous ligand-nociceptin/orphanin FQ
    Henderson, G
    McKnight, AT
    TRENDS IN PHARMACOLOGICAL SCIENCES, 1997, 18 (08) : 293 - 300
  • [22] Assessment of nociceptin/orphanin FQ and μ-opioid receptor mRNA in the human right atrium
    McDonald, J.
    Leonard, A. D.
    Serrano-Gomez, A.
    Young, S. P.
    Swanevelder, J.
    Thompson, J. P.
    Lambert, D. G.
    BRITISH JOURNAL OF ANAESTHESIA, 2010, 104 (06) : 698 - 704
  • [23] Functional expression of opioid receptor-like receptor and its endogenous specific agonist nociceptin/orphanin FQ during mouse embryogenesis
    Wu Y.L.
    Fan G.H.
    Zhao J.
    Zhang Y.
    Zhou T.H.
    Ma L.
    Pei G.
    Cell Research, 1997, 7 (2) : 207 - 215
  • [24] Heterodimerization of mu opioid receptor and nociceptin/orphanin FQ peptide receptor alters g protein coupling
    Gunduz, O.
    Baldini, E.
    Borsodi, A.
    Benyhe, S.
    Corbani, M.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2009, 19 : S280 - S281
  • [25] Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems
    Toll, Lawrence
    Bruchas, Michael R.
    Calo', Girolamo
    Cox, Brian M.
    Zaveri, Nurulain T.
    PHARMACOLOGICAL REVIEWS, 2016, 68 (02) : 419 - 457
  • [26] Investigating Arrestin-3 Recruitment to Nociceptin/Orphanin FQ Opioid Receptor (NOPR)
    Hansen, Marissa M.
    Spangler, Skylar M.
    Bruchas, Michael R.
    FASEB JOURNAL, 2018, 32 (01):
  • [27] Distribution of nociceptin orphanin FQ receptor transcript in human
    Peluso, J
    Matthes, H
    Höllt, V
    EUROPEAN JOURNAL OF NEUROSCIENCE, 1998, 10 : 75 - 75
  • [28] NOCICEPTIN/ORPHANIN FQ RECEPTOR AGONISTS AS SPINAL ANALGESICS
    Calo, Girolamo
    NEUROPEPTIDES, 2010, 44 (06) : 531 - 531
  • [29] Spotlight on Nociceptin/Orphanin FQ Receptor in the Treatment of Pain
    El Daibani, Amal
    Che, Tao
    MOLECULES, 2022, 27 (03):
  • [30] Expression of nociceptin/orphanin FQ and nociceptin receptor in the patients with ulcerative colitis
    Kato, S.
    Itoh, K.
    Miura, S.
    Yakabi, K.
    REGULATORY PEPTIDES, 2006, 135 (03) : 135 - 135
12345