Effect of smoking and aging on micronucleus frequencies in human exfoliated buccal cells

被引:0
|
作者
Konopacka, M [1 ]
机构
[1] Inst Oncol, Dept Expt & Clin Radiobiol, PL-44100 Gliwice, Poland
关键词
micronuclei; exfoliated buccal cells; smoking; aging;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In the present work the frequency of micronuclei (MN) in exfoliated buccal cells in 120 healthy individuals with relation to sex, age and smoking was investigated. Neither age nor sex showed any effect on the level of micronuclei. Smoking has shown a significant effect upon basal DNA damage. In the present study the calculated background frequency of micronuclei (parts per thousand) in oral epithelial cells of 50 smokers and 70 non-smokers were 1.50 (+/-0.47) and 0.55 (+/-0.32), respectively.
引用
收藏
页码:380 / 382
页数:3
相关论文
共 50 条
  • [41] EFFECT OF SMOKING ON FOLATE LEVELS IN BUCCAL MUCOSAL CELLS
    PIYATHILAKE, CJ
    HINE, RJ
    DASANAYAKE, AP
    RICHARDS, EW
    FREEBERG, LE
    VAUGHN, WH
    KRUMDIECK, CL
    INTERNATIONAL JOURNAL OF CANCER, 1992, 52 (04) : 566 - 569
  • [42] The effect of maras powder on DNA methylation and micronucleus formation in human buccal tissue
    Saatci, Cetin
    Ozkul, Yusuf
    Tahiri, Serpil
    Caglayan, Ahmet Okay
    Turhan, Ahmet Bulent
    Dundar, Munis
    JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2008, 71 (06): : 396 - 404
  • [43] Micronucleus assay of buccal mucosa cells in smokers with the history of smoking less and more than 10 years
    Naderi, Noushin Jalayer
    Farhadi, Sareh
    Sarshar, Samaneh
    INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2012, 55 (04) : 433 - 438
  • [44] The micronucleus assay in exfoliated human cells: A mini-review of papers from the CIS
    Nersesyan, A. K.
    Ilin, A. I.
    CYTOLOGY AND GENETICS, 2007, 41 (02) : 115 - 124
  • [45] The micronucleus assay in exfoliated human cells: A mini-review of papers from the CIS
    A. K. Nersesyan
    A. I. Ilin
    Cytology and Genetics, 2007, 41 : 115 - 124
  • [46] Effect of mobile phones on micronucleus frequency in human exfoliated oral mucosal cells (vol 18, pg 786, 2012)
    Ros-Llor, I.
    Sanchez-Siles, M.
    Camacho-Alonso, F.
    Lopez-Jornet, P.
    ORAL DISEASES, 2013, 19 (01) : 109 - 110
  • [47] Comparison of Genotoxic Effect in Buccal Exfoliated Cells between Cigarette and Waterpipe Smokers
    Rajabi-Moghaddam, Mahdieh
    Haji Mirzamohammad, Mohammad
    Yahyazadeh, Elham
    Gholinia, Hemmat
    Abbaszadeh, Hamid
    ACTA CYTOLOGICA, 2020, 64 (05) : 471 - 476
  • [48] Harmonisation of the micronucleus assay in human buccal cells -: a Human Micronucleus (HUMN) project (www.humn.org) initiative commencing in 2007
    Fenech, Michael
    Bolognesi, Claudia
    Kirsch-Volders, Micheline
    Bonassi, Stefano
    Zeiger, Errol
    Knasmueller, Siegfried
    Holland, Nina
    MUTAGENESIS, 2007, 22 (01) : 3 - 4
  • [49] Assessment of micronucleus frequency in exfoliated buccal epithelial cells among fisher folks exposed to mine tailings in Marinduque Island,Philippines
    Elena M Ragragio
    Celeste P Belleza
    Mark C Narciso
    Glenn L Sia Su
    Asian Pacific Journal of Tropical Medicine, 2010, 3 (04) : 315 - 317
  • [50] Assessment of micronucleus frequency in exfoliated buccal epithelial cells among fisher folks exposed to mine tailings in Marinduque Island, Philippines
    Ragragio, Elena M.
    Belleza, Celeste P.
    Narciso, Mark C.
    Su, Glenn L. Sia
    ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2010, 3 (04) : 315 - 315