Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla

被引：12

作者：

Brkljaca, Robert ^{[1
]}

Goeker, Emrehan Semih ^{[1
]}

Urban, Sylvia ^{[1
]}

机构：

[1] RMIT Univ, Sch Appl Sci, Discipline Chem, HIRi, Melbourne, Vic 3001, Australia

来源：

MARINE DRUGS | 2015年 / 13卷 / 05期

关键词：

ochrophyta; rhodophyta; dereplication; profiling; algae; HPLC-NMR; HPLC-MS; LAURENCIA-FILIFORMIS; CAULOCYSTIS-CEPHALORNITHOS; CYSTOPHORA-RETROFLEXA; C-15; ACETOGENIN; FUCOXANTHIN; METABOLITES; CAROTENOIDS; NMR; FUCOPHLORETHOLS; SESQUITERPENE;

D O I：

10.3390/md13052714

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Dereplication and chemotaxonomic studies of six marine algae of the Ochrophyta and one of the Rhodophyta phyla resulted in the detection of 22 separate compounds. All 16 secondary metabolites, including four new compounds (16-19), could be rapidly dereplicated using HPLC-NMR and HPLC-MS methodologies in conjunction with the MarinLit database. This study highlights the advantages of using NMR data (acquired via HPLC-NMR) for database searching and for the overall dereplication of natural products.

引用

页码：2714 / 2731

页数：18

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