Imaging Biomarkers in Lung Cancer with 68Ga-DOTATATE, 18F-Fluoride, and 18F-FDG PET/CT Scans and the Theranostics Paradigm

被引:3
|
作者
Djekidel, Mehdi [1 ]
Syed, Ghulam [2 ]
Kanbour, Aladdin [3 ]
机构
[1] Hamad Med Corp, NCCCR, Div Oncol, Doha, Qatar
[2] Hamad Med Corp, Div Nucl Med, Dept Radiol, Doha, Qatar
[3] Sidra Med, Div Nucl Med, Dept Radiol, Doha, Qatar
关键词
lung cancer; lung adenocarcinoma; F-18-FDG; Ga-68-DOTATATE; F-18-fluoride; theranostics; ALPHA EMITTER RADIUM-223; CELL; CARCINOMA; BIODISTRIBUTION; COMBINATION; SURVIVAL;
D O I
10.2967/jnmt.120.258343
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Lung cancer is the number 1 cause of cancer deaths in the United States. The prognosis is quite grim with the exception of stage 1. When faced with several failed therapeutic regimens and rapid progression of the disease, considering alternative therapies such as radiopharmaceutical therapies may be an option. We describe the case of a 36-y-old man with lung adenocarcinoma who had imaging molecular characterization of his disease with F-18-FDG, Ga-68-DOTATATE, and F-18-fluoride PET/CT scans that were able to shed some light on molecular characterization of his disease and serve as a guide to potential targeted or personalized radiopharmaceutical therapeutic options.
引用
收藏
页码:281 / 283
页数:3
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