Imaging Biomarkers in Lung Cancer with 68Ga-DOTATATE, 18F-Fluoride, and 18F-FDG PET/CT Scans and the Theranostics Paradigm

被引：3

作者：

Djekidel, Mehdi ^{[1
]}

Syed, Ghulam ^{[2
]}

Kanbour, Aladdin ^{[3
]}

机构：

[1] Hamad Med Corp, NCCCR, Div Oncol, Doha, Qatar

[2] Hamad Med Corp, Div Nucl Med, Dept Radiol, Doha, Qatar

[3] Sidra Med, Div Nucl Med, Dept Radiol, Doha, Qatar

来源：

JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY | 2021年 / 49卷 / 03期

关键词：

lung cancer; lung adenocarcinoma; F-18-FDG; Ga-68-DOTATATE; F-18-fluoride; theranostics; ALPHA EMITTER RADIUM-223; CELL; CARCINOMA; BIODISTRIBUTION; COMBINATION; SURVIVAL;

D O I：

10.2967/jnmt.120.258343

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Lung cancer is the number 1 cause of cancer deaths in the United States. The prognosis is quite grim with the exception of stage 1. When faced with several failed therapeutic regimens and rapid progression of the disease, considering alternative therapies such as radiopharmaceutical therapies may be an option. We describe the case of a 36-y-old man with lung adenocarcinoma who had imaging molecular characterization of his disease with F-18-FDG, Ga-68-DOTATATE, and F-18-fluoride PET/CT scans that were able to shed some light on molecular characterization of his disease and serve as a guide to potential targeted or personalized radiopharmaceutical therapeutic options.

引用

页码：281 / 283

页数：3

共 50 条

[1] 68Ga-DOTATATE and 18F-FDG PET/CT in a Rapidly Progressing Lymphoma
Parihar, Ashwin Singh
Wahl, Richard L.
Jahromi, Amin H.
CLINICAL NUCLEAR MEDICINE, 2025, 50 (01) : e64 - e65
[2] A Case of Brown Tumor on 68Ga-DOTATATE PET/CT and 18F-FDG PET/CT
Yao, Xilan
Ou, Xiaohong
CLINICAL NUCLEAR MEDICINE, 2022, 47 (01) : 88 - 89
[3] 68Ga-DOTATATE and 18F-FDG PET/CT for the Management of Esthesioneuroblastoma of the Sphenoclival Region
Dadgar, Habibollah
Norouzbeigi, Nasim
Ahmadzadehfar, Hojjat
Assadi, Majid
CLINICAL NUCLEAR MEDICINE, 2020, 45 (08) : E363 - E364
[4] A Comparison of 68Ga-DOTATATE and 18F-FDG PET/CT in Pulmonary Neuroendocrine Tumors
Kayani, Irfan
Conry, Brendon G.
Groves, Ashley M.
Win, Thida
Dickson, John
Caplin, Martyn
Bomanji, Jamshed B.
JOURNAL OF NUCLEAR MEDICINE, 2009, 50 (12) : 1927 - 1932
[5] 68Ga-DOTATATE and 18F-FDG in Castleman Disease
Vercosa, Alinne Fernanda Amaral
Flamini, Maria Eduarda Duarte de Mello
Loureiro, Luiz Victor Maia
Flamini, Rodrigo de Carvalho
CLINICAL NUCLEAR MEDICINE, 2020, 45 (11) : 868 - 870
[6] Concurrent Metastatic Pheochromocytomas and Lung Adenocarcinoma on 18F-FDG and 68Ga-DOTATATE PET/CT Images
Cheng, Zhaoting
Zou, Sijuan
Song, Shuang
Zhu, Xiaohua
CLINICAL NUCLEAR MEDICINE, 2019, 44 (09) : 754 - 756
[7] 68Ga-DOTATATE PET Outperforms 18F-FDG PET for Imaging Vascular Inflammation in Atherosclerosis
Tarkin, Jason M.
Joshi, Francis R.
Evans, Nicholas R.
Chowdhury, Mohammed M.
Figg, Nichola L.
Shah, Aarti V.
Starks, Lakshi T.
Manavaki, Roie
Martin-Garrido, Abel
Yu, Emma
Kuc, Rhoda E.
Kreuzhuber, Luigi Grassi Roman
Kostadima, Myrto
Frontini, Mattia
Ouwehand, Willem H.
Groves, Ashley M.
Gopalan, Deepa
Kirkpatrick, Peter J.
Coughlin, Patrick A.
Buscombe, John R.
Fryer, Tim D.
Bennett, Martin R.
Warburton, Elizabeth A.
Davenport, Anthony P.
Rudd, James H.
CIRCULATION, 2016, 134
[8] Comparison of 18F-FDG PET/CT and 68Ga-DOTATATE PET/CT Imaging in Metastasized Merkel Cell Carcinoma
Epstude, Maximilian
Tornquist, Katharina
Riklin, Christian
di Lenardo, Francesca
Winterhalder, Ralph
Hug, Urs
Strobel, Klaus
CLINICAL NUCLEAR MEDICINE, 2013, 38 (04) : 283 - 284
[9] Differentiation of sellar lesions by use of combination of 68Ga-DOTATATE and 18F-FDG PET/CT
Zhao, Xiaobin
Xiao, Jianqi
Xing, Bing
Wang, Renzhi
Li, Fang
Zhu, Zhaohui
JOURNAL OF NUCLEAR MEDICINE, 2014, 55
[10] 68Ga-DOTATATE and 18F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity
Chang, Chian A.
Pattison, David A.
Tothill, Richard W.
Kong, Grace
Akhurst, Tim J.
Hicks, Rodney J.
Hofman, Michael S.
CANCER IMAGING, 2016, 16

← 1 2 3 4 5 →