ELECTROSTATIC SWITCHING BIOSENSOR - A NOVEL LABEL-FREE DNA DETECTION USING AN ELECTRODE CHARGING TECHNIQUE

被引：0

作者：

Hwang, Sung-Up ^{[1
]}

Choi, Ji-Min ^{[1
]}

Yang, Hyun-Ho ^{[1
]}

Kim, Chang-Hoon ^{[1
]}

Jung, Chulhee

Park, Hyun Gyu

Choi, Yang-Kyu ^{[1
]}

Yoon, Jun-Bo ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Elect Engn, 373-1 Guseong Dong, Taejon 305701, South Korea

来源：

2011 IEEE 24TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS) | 2011年

基金：

新加坡国家研究基金会;

关键词：

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This paper reports a novel electrical detection of label-free DNA by use of a MEMS electrostatic micro-switch. The electrostatic micro-switch detects the immobilization of probe oligonucleotides and their hybridization with target oligonucleotides using pull-in voltage shift in the micro-switch originated from negative charges of the oligonucleotides. A numerical simulation is analyzed to support this concept. The proposed biomolecule detection method using an electrostatic micro-switch represents a protocol for a new candidate of microactuator-type sensor.

引用

页码：857 / 860

页数：4

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