ELECTROSTATIC SWITCHING BIOSENSOR - A NOVEL LABEL-FREE DNA DETECTION USING AN ELECTRODE CHARGING TECHNIQUE

被引：0
|
作者：
Hwang, Sung-Up [1 ]
Choi, Ji-Min [1 ]
Yang, Hyun-Ho [1 ]
Kim, Chang-Hoon [1 ]
Jung, Chulhee
Park, Hyun Gyu
Choi, Yang-Kyu [1 ]
Yoon, Jun-Bo [1 ]
机构：
[1] Korea Adv Inst Sci & Technol, Dept Elect Engn, 373-1 Guseong Dong, Taejon 305701, South Korea
来源：
2011 IEEE 24TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS) | 2011年
基金：
新加坡国家研究基金会;
关键词：
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
This paper reports a novel electrical detection of label-free DNA by use of a MEMS electrostatic micro-switch. The electrostatic micro-switch detects the immobilization of probe oligonucleotides and their hybridization with target oligonucleotides using pull-in voltage shift in the micro-switch originated from negative charges of the oligonucleotides. A numerical simulation is analyzed to support this concept. The proposed biomolecule detection method using an electrostatic micro-switch represents a protocol for a new candidate of microactuator-type sensor.
引用
收藏
页码：857 / 860
页数：4
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