Mitochondrial diseases and the role of the yeast models

被引：34

作者：

Rinaldi, Teresa ^{[2
]}

Dallabona, Cristina ^{[3
]}

Ferrero, Ileana ^{[3
]}

Frontali, Laura ^{[2
]}

Bolotin-Fukuhara, Monique ^{[1
]}

机构：

[1] Univ Paris 11, Inst Genet & Microbiol, CNRS, F-91405 Orsay, France

[2] Univ Roma La Sapienza, Dept Cell & Dev Biol, Inst Pasteur, Cenci Bolognetti Fdn, Rome, Italy

[3] Univ Parma, Dept Genet, I-43100 Parma, Italy

来源：

FEMS YEAST RESEARCH | 2010年 / 10卷 / 08期

关键词：

mitochondrial diseases; fusion; fission; mitochondrial transformation; mitochondrial tRNAs; mtDNA stability and maintenance; DYNAMIN-RELATED GTPASE; DNA-POLYMERASE-GAMMA; PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; DIFFERENTIATION-ASSOCIATED PROTEIN-1; ADENINE-NUCLEOTIDE TRANSLOCATOR; CYTOCHROME-B MUTATIONS; DOMINANT OPTIC ATROPHY; SACCHAROMYCES-CEREVISIAE; SUCCINATE-DEHYDROGENASE; MEMBRANE PROTEIN;

D O I：

10.1111/j.1567-1364.2010.00685.x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Nowadays, mitochondrial diseases are recognized and studied with much attention and they cannot be considered anymore as 'rare diseases'. Yeast has been an instrumental organism to understand the genetic and molecular aspects of the many roles of mitochondria within the cells. Thanks to the general conservation of mitochondrial genes and pathways between human and yeast, it can also be used to model some diseases. In this review, we focus on the most recent topics, exemplifying those for which yeast models have been especially valuable.

引用

页码：1006 / 1022

页数：17

共 50 条

[21] Role of Mitochondrial Dynamics in Heart Diseases
Tokuyama, Takeshi
Yanagi, Shigeru
GENES, 2023, 14 (10)
[22] Role of mitochondrial dysfunction on rheumatic diseases
Vaamonde-Garcia, Carlos
Lopez-Armada, Maria J.
BIOCHEMICAL PHARMACOLOGY, 2019, 165 : 181 - 195
[23] Models of the Transmembrane Domains of the Yeast Mitochondrial CitrateTransport Protein
D. Eric Walters
Ronald S. Kaplan
Molecular modeling annual, 2000, 6 : 587 - 594
[24] The control of mitochondrial respiration in yeast: A possible role of the outer mitochondrial membrane
Ahmadzadeh, M
Horng, A
Colombini, M
CELL BIOCHEMISTRY AND FUNCTION, 1996, 14 (03) : 201 - 208
[25] ROLE OF THE YEAST MITOCHONDRIAL GENE PRODUCT VARL IN MITOCHONDRIAL RIBOSOME ASSEMBLY
BUTOW, RA
TERPSTRA, P
FEDERATION PROCEEDINGS, 1979, 38 (03) : 227 - 227
[26] Human mitochondrial DNA diseases and Drosophila models
Chen, Zhe
Zhang, Fan
Xu, Hong
JOURNAL OF GENETICS AND GENOMICS, 2019, 46 (04) : 201 - 212
[27] Cell models and drug discovery for mitochondrial diseases
Hu, Shuang-yi
Zhuang, Qian-qian
Qiu, Yue
Zhu, Xu-fen
Yan, Qing-feng
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2019, 20 (05): : 449 - 456
[28] Human mitochondrial DNA diseases and Drosophila models
Zhe Chen
Fan Zhang
Hong Xu
JournalofGeneticsandGenomics, 2019, 46 (04) : 201 - 212
[29] Yeast Models and Molecular Mechanisms of Neurodegenerative Diseases 2.0
Kaminska, Joanna
Zoladek, Teresa
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (24)
[30] Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases
Suarez-Rivero, Juan M.
Pastor-Maldonado, Carmen J.
Romero-Gonzalez, Ana
Gomez-Fernandez, David
Povea-Cabello, Suleva
Alvarez-Cordoba, Monica
Villalon-Garcia, Irene
Talaveron-Rey, Marta
Suarez-Carrillo, Alejandra
Munuera-Cabeza, Manuel
Sanchez-Alcazar, Jose A.
FRONTIERS IN PHARMACOLOGY, 2022, 13

← 1 2 3 4 5 →