Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients

被引：5

作者：

Orr, Hillary ^{[1
,2
]}

Trone, Deni ^{[1
,3
]}

Elder, Joshua ^{[1
]}

Raj, Ashok ^{[4
]}

机构：

[1] Norton Childrens Hosp, Dept Pharm, Louisville, KY 40202 USA

[2] Childrens Mem Hermann Hosp, Dept Pharm, 6411 Fannin St, Houston, TX 77030 USA

[3] St Jude Childrens Res Hosp, Dept Pharm, 262 Danny Thomas Pl, Memphis, TN 38105 USA

[4] Univ Louisville, Div Pediat Hematol Oncol, Louisville, KY 40202 USA

来源：

CHILDREN-BASEL | 2017年 / 4卷 / 09期

关键词：

vancomycin; pediatrics; oncology; pharmacokinetics; DOSAGE;

D O I：

10.3390/children4090079

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This was a retrospective audit assessing vancomycin dosing of 60 mg/kg/day in the attainment of therapeutic concentrations between 10-20 mcg/mL among 56 pediatric oncology patients. Twelve patients (21%) achieved therapeutic concentrations of 10-20 mcg/mL, while 44 patients (79%) obtained trough levels below 10 mcg/mL despite the addition of nephrotoxic agents.

引用

页数：4

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