Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients

被引:5
|
作者
Orr, Hillary [1 ,2 ]
Trone, Deni [1 ,3 ]
Elder, Joshua [1 ]
Raj, Ashok [4 ]
机构
[1] Norton Childrens Hosp, Dept Pharm, Louisville, KY 40202 USA
[2] Childrens Mem Hermann Hosp, Dept Pharm, 6411 Fannin St, Houston, TX 77030 USA
[3] St Jude Childrens Res Hosp, Dept Pharm, 262 Danny Thomas Pl, Memphis, TN 38105 USA
[4] Univ Louisville, Div Pediat Hematol Oncol, Louisville, KY 40202 USA
来源
CHILDREN-BASEL | 2017年 / 4卷 / 09期
关键词
vancomycin; pediatrics; oncology; pharmacokinetics; DOSAGE;
D O I
10.3390/children4090079
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
This was a retrospective audit assessing vancomycin dosing of 60 mg/kg/day in the attainment of therapeutic concentrations between 10-20 mcg/mL among 56 pediatric oncology patients. Twelve patients (21%) achieved therapeutic concentrations of 10-20 mcg/mL, while 44 patients (79%) obtained trough levels below 10 mcg/mL despite the addition of nephrotoxic agents.
引用
收藏
页数:4
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