Unravelling the mystery of female meiotic drive: where we are

被引:26
|
作者
Clark, Frances E. [1 ]
Akera, Takashi [1 ]
机构
[1] NHLBI, Cell & Dev Biol Ctr, NIH, Bldg 10, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
meiotic drive; female meiosis; chromosome segregation; selfish genetic elements; B-CHROMOSOMES; NONRANDOM SEGREGATION; ZEBRA FINCH; EVOLUTION; CENTROMERE; TRANSMISSION; MEIOSIS; SEX; RATES; BODY;
D O I
10.1098/rsob.210074
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Female meiotic drive is the phenomenon where a selfish genetic element alters chromosome segregation during female meiosis to segregate to the egg and transmit to the next generation more frequently than Mendelian expectation. While several examples of female meiotic drive have been known for many decades, a molecular understanding of the underlying mechanisms has been elusive. Recent advances in this area in several model species prompts a comparative re-examination of these drive systems. In this review, we compare female meiotic drive of several animal and plant species, highlighting pertinent similarities.
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收藏
页数:14
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