7"-benzyl-9"-benzylidene-4′-[4-(dimethylamino)-phenyl]-1′-methyl-5"-phenyl-2",3",6",7",8",9"-hexa-hydro-1H-indole-3(2H)-spiro-2′-pyrimidine-3′-spiro-2"-pyrido[4,3-d]thiazolo[3,2-a]pyrimidine-2,2"-dione acetonitrile disolvate

被引:1
|
作者
Hu, XF [1 ]
Feng, YQ [1 ]
Su, Q [1 ]
Qiao, KJ [1 ]
机构
[1] Tianjin Univ, Sch Chem Eng & Technol, Tianjin 300072, Peoples R China
关键词
D O I
10.1107/S1600536805015485
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The title compound, C48H44N6O2S center dot 2C(2)H(3)N, was synthesized by the intermolecular [3+2]-cycloaddition of an azomethine ylide, derived from isatin and sarcosine by a decarboxylative route, and 7-benzyl-9-benzylidene-2-[4-(dimethylamino)benzylidene]-5-phenyl-2,3,6,7,8,9-hexahydro-5H-pyrido[4,3-d]thiazolo[3,2-a]pyrimidin-3-one. In the molecule, the two spiro junctions link a planar 2-oxindole system, a pyrrolidine ring in an envelope conformation and a thiazolidone ring of the fused pyrimidine ring system. The packing of the molecules in the crystal structure is mainly stabilized by N-(HO)-O-... hydrogen bonds.
引用
收藏
页码:O1830 / O1832
页数:3
相关论文
共 50 条
  • [21] A NOVEL SPIRO SYSTEM - 4',7'-DIHYDRO-8'-PHENYL SPIRO[H-3-INDOLE-3,6'-[PYRAZOLO(3,2-D)-1,3,5-THIADIAZEPINE]]-2,3'(H-1)DIONE
    JOSHI, KC
    CHAND, P
    DANDIA, A
    HETEROCYCLES, 1984, 21 : 526 - 526
  • [22] 1′-methyl-4′-phenyl-H-fluorene-9-spiro-3′-pyrrolidine-2′-spiro-3"-1H-indol-2"(3"H)-one
    Aravindan, PG
    Selvanayagam, S
    Velmurugan, D
    Ravikumar, K
    Jayashankaran, J
    Raghunathan, R
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2004, 60 : O2152 - O2154
  • [23] 1′-methyl-4′-(2,4-dichlorophenyl)-1H-indole-3-spiro-2′-pyrrolidine-3′-spiro-5"-(thiazolo[3,2-b][1,2,4]triazole)-2.6"(3H,5"H)-dione
    Li, XF
    Feng, YQ
    Yao, GY
    You, XD
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2003, 59 : O1810 - O1811
  • [24] Crystal structure of ethyl 5"-(2,4-dichloroyphenyl)-1′-methyl-4-carboxylic acid methyl ester-2,3"-dioxo-2,3,2",3"-tetrahydro-1H-indole-3-spiro-2′-pyrrolidine-3′-spiro-2"-thiazolo[3",2"-a]-pyrimidine-6"-carboxylate, C29H26Cl2N4O6S
    Ling, Yulin
    Li, Xiaofang
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2009, 224 (02): : 335 - 336
  • [25] An Efficient Synthesis of 6′-methyl-1′H-spiro[indoline-3,4′-pyrimidine]-2,2′(3′H)-dione Derivatives
    Gao, Lijiu
    Qin, Yaqi
    Yu, Qiuyu
    Ling, Zhi
    Xu, Zhongyun
    Rong, Liangce
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 54 (06) : 3258 - 3264
  • [26] SYNTHESIS OF NEW 3-BENZYL-5-PHENYL-7-ALKYLAMINOTHIAZOLO[4,5-D]PYRIMIDINE-2(3H)-THIONES
    BIAGI, G
    GIORGI, I
    LIVI, O
    SCARTONI, V
    FARMACO, 1995, 50 (09): : 579 - 586
  • [27] (4S)-4-(3,4-Dichlorophenyl)-1′-methyl-4′-phenyl-3,4-dihydronaphthalene-2-spiro-3′-pyrrolidine-2′-spiro-1"-acenaphthylene-1,2"(2H,1"H)-dione
    Murugan, R.
    Gunasekaran, B.
    Narayanan, S. Sriman
    Manivannan, V.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1089 - U2281
  • [28] 4′-(2,4-dichlorophenyl)-1′-methyl-2,3,2",3"-tetrahydro-1H-indole-3-spiro-2′-pyrrolidine-3′-spiro-2"-(1,3-benzimidazo[2,1-b]thiazole)-2,3"-dione
    Li, XF
    Feng, YQ
    Shi, DX
    Chen, HL
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2003, 59 : O1405 - O1406
  • [29] 1′-methyl-5-diphenyl-4′-p-tolyl-5,6,7,8,9,10-hexahydro1,3-cycloheptapyrimidino[2,3-b]thiazole-2-spiro-3′-pyrrolidine-2′-spiro-3"-1H-indole-2",3(2H,3"H)-dione
    Gayathri, D.
    Velmurugan, D.
    Ravikumar, K.
    Poornachandran, M.
    Raghunathan, R.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O5658 - O5660
  • [30] 1′-methyl-5-diphenyl-4′-p-tolyl-5,6,7,8,9,10-hexahydro-1,3-cyclooctapyrimidino[2,3-b]thiazole-2-spiro-3′-pyrrolidine-2′-spiro-3"-1H-indole-2",3(2H,3"H)dione
    Gayathri, D.
    Velmurugan, D.
    Ravikumar, K.
    Poornachandran, M.
    Raghunathan, R.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O5661 - O5663